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Methoxyphenidine

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Identification
Molecular formula
C20H24N2O3
CAS number
83156-05-8
IUPAC name
2-(diethylamino)ethyl 5-methoxy-2-methyl-1-phenyl-indole-3-carboxylate
State
State

At room temperature, Methoxyphenidine exists as a crystalline solid. Its stability in solid-state form allows it to be stored easily under controlled conditions.

Melting point (Celsius)
104.00
Melting point (Kelvin)
377.15
Boiling point (Celsius)
314.20
Boiling point (Kelvin)
587.35
General information
Molecular weight
342.44g/mol
Molar mass
342.4390g/mol
Density
1.2111g/cm3
Appearence

Methoxyphenidine is typically a solid and can be found in a crystalline powder form. The color of the crystals ranges from off-white to a slightly amber shade, depending on the purity and preparation. The texture of the powder can be fine and fluffy, suitable for laboratory handling and chemical processes. It is important to use protective gear while handling it, as it can pose health risks upon exposure.

Comment on solubility

Solubility Profile of 2-(Diethylamino)ethyl 5-Methoxy-2-Methyl-1-Phenyl-Indole-3-Carboxylate

The solubility of 2-(diethylamino)ethyl 5-methoxy-2-methyl-1-phenyl-indole-3-carboxylate is an intriguing topic due to its organic nature and the presence of multiple functional groups. Here are key considerations regarding its solubility:

  • Solvent Dependence: This compound's solubility is highly dependent on the solvent used. It is generally more soluble in organic solvents such as ethanol, dichloromethane, and dimethyl sulfoxide.
  • Polarity: The presence of the diethylamino group contributes to its polar character, which can enhance solubility in polar solvents, while its aromatic structure favors solubility in nonpolar solvents.
  • pH Influence: Changes in pH may also alter the solubility. In acidic conditions, the carboxylate group can be protonated, potentially increasing solubility in aqueous solutions.

In general, when evaluating the solubility of this compound, it is important to consider the following:

  1. Type of solvent: polar vs. nonpolar
  2. Temperature: higher temperatures can often increase solubility
  3. Concentration of other solutes in the solution

In summary, while 2-(diethylamino)ethyl 5-methoxy-2-methyl-1-phenyl-indole-3-carboxylate exhibits variable solubility characteristics, its overall behavior can be understood through the lens of its molecular structure and the interactions with the surrounding solvent environment. Understanding these nuances can be critical for applications in fields such as pharmaceuticals and organic synthesis.

Interesting facts

Exploring 2-(Diethylamino)ethyl 5-Methoxy-2-Methyl-1-Phenyl-Indole-3-Carboxylate

2-(Diethylamino)ethyl 5-methoxy-2-methyl-1-phenyl-indole-3-carboxylate is a fascinating compound that belongs to the class of indole derivatives, which are known for their diverse biological activities and medicinal properties. Here are some intriguing points about this compound:

  • Pharmacological Potential: Compounds in the indole family often display significant pharmacological effects. Research has suggested that this compound may possess antidepressant and analgesic properties, making it of interest for therapeutic applications.
  • Structure-Activity Relationship (SAR): The unique structural features, such as the diethylamino group and the methoxy substitution, can influence the biological activity of this compound, paving the way for optimization in drug design.
  • Synthetic Pathways: Understanding the synthesis of this compound can enhance our knowledge of organic synthesis techniques, particularly in manipulations involving indoles and amines. This compound can serve as a model for developing new synthetic methodologies.
  • Natural Occurrences: Indoles are commonly found in various natural products, including alkaloids and plant metabolites. This compound's indole structure may help researchers explore similar compounds available in nature.
  • Applications in Research: Due to its potential bioactivity, this compound is likely to attract attention in both medicinal chemistry and pharmacology research, providing a platform for studying complex biological interactions.

With these properties and its promising potential, 2-(diethylamino)ethyl 5-methoxy-2-methyl-1-phenyl-indole-3-carboxylate exemplifies the richness found in the realm of chemical compounds. As research continues, it may lead to the development of innovative therapeutic agents.