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Neostigmine

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Identification
Molecular formula
C12H19BrN2O2
CAS number
59-99-4
IUPAC name
2-(diethylamino)ethyl 9-hydroxyfluorene-9-carboxylate
State
State

At room temperature, neostigmine is a solid. When it is used in a clinical setting, it is often administered in a liquid form as an injectable solution.

Melting point (Celsius)
140.00
Melting point (Kelvin)
413.00
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.00
General information
Molecular weight
303.37g/mol
Molar mass
303.3650g/mol
Density
1.0800g/cm3
Appearence

Neostigmine is typically found as a white crystalline powder. It is often utilized in its methylsulfate form which dissolves in water to form a clear colorless solution. It is odorless and can be hygroscopic depending on its formulation.

Comment on solubility

Solubility Insights on 2-(diethylamino)ethyl 9-hydroxyfluorene-9-carboxylate

2-(diethylamino)ethyl 9-hydroxyfluorene-9-carboxylate is a fascinating compound with unique solubility characteristics. Here are some key points to consider:

  • Polarity: The presence of the diethylamino group adds a level of polarity to the molecule, potentially enhancing its solubility in polar solvents such as water.
  • Hydrophobicity: The fluorene structure is largely hydrophobic, which may hinder its solubility in polar environments while promoting better solubility in *non-polar solvents* like organic solvents.
  • pH Influence: As a carboxylate, the solubility of this compound can be affected by the pH of the environment, where it may exhibit better solubility in basic conditions.

In summary, the solubility of 2-(diethylamino)ethyl 9-hydroxyfluorene-9-carboxylate is a balance between its hydrophilic and hydrophobic parts. It may be soluble in:

  1. Polar solvents (to some extent due to the amino group)
  2. Organic solvents (due to the hydrophobic fluorene structure)

Understanding the solubility profile of this compound is crucial for its application in various fields, especially in organic chemistry settings where solvent choice significantly impacts reaction outcomes.

Interesting facts

Interesting Facts About 2-(diethylamino)ethyl 9-hydroxyfluorene-9-carboxylate

2-(diethylamino)ethyl 9-hydroxyfluorene-9-carboxylate is a fascinating compound that combines organic chemistry with fascinating applications in various fields. Here are some engaging insights about this compound:

  • Structure and Function: The structure of this compound features a *fluorene* ring, which is known for its unique electronic properties. These properties enable it to function as a *fluorescent dye*, making it valuable in the field of photonics.
  • Biological Significance: The functional groups in this compound suggest potential biological activity. Investigations into such compounds have shown promise in medicinal chemistry, particularly in drug design where targets may include specific enzymes or receptors.
  • Synthesis and Reactions: The synthesis of 2-(diethylamino)ethyl 9-hydroxyfluorene-9-carboxylate often involves a combination of *condensation* and *functionalization* reactions. This makes it a good candidate for studying reaction mechanisms and optimizing synthetic methodologies.
  • Applications: Beyond its role as a fluorescent dye, this compound can serve as a *precursor* for developing other complex organic molecules. Its derivatives have found applications in the creation of *materials* with specific optical properties and in *organic light-emitting diodes (OLEDs)*.
  • Research and Innovation: The unique properties of this compound inspire ongoing research. Scientists are constantly exploring new ways to utilize its characteristics, such as enhancing *energy efficiency* or improving *photostability* in applications like organic photovoltaics.

Overall, 2-(diethylamino)ethyl 9-hydroxyfluorene-9-carboxylate illustrates the intricate relationship between structure and function in organic chemistry, providing a platform for innovation and discovery in diverse scientific arenas. As one researcher aptly noted, "Each compound tells a story through its structure, waiting for us to uncover its secrets."

Synonyms
BRN 0928642
2-(Diethylamino)ethyl 9-hydroxy-9-fluorenecarboxylate
24539-81-9
9-FLOURENECARBOXYLIC ACID, 9-HYDROXY-, 2-(DIETHYLAMINO)ETHYL ESTER
9-Hydroxy-9-fluorenecarboxylic acid 2-(diethylamino)ethyl ester
DTXSID80179283
3-10-00-01251 (Beilstein Handbook Reference)
RefChem:313117
DTXCID10101774
2-diethylaminoethyl 9-hydroxyfluorene-9-carboxylate
ALBB-035686
AKOS040766809