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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(diethylamino)ethyl benzoate
State
State

Procaine is typically found in a solid state at room temperature.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
431.10
Boiling point (Kelvin)
704.30
General information
Molecular weight
180.25g/mol
Molar mass
180.2450g/mol
Density
1.1000g/cm3
Appearence

Procaine is a white crystalline powder. It is odorless, and has a slightly bitter taste followed by a numbing sensation. As a hydrochloride salt, it is more stable and used in medical applications.

Comment on solubility

Solubility of 2-(diethylamino)ethyl benzoate

2-(diethylamino)ethyl benzoate is an intriguing compound when it comes to its solubility properties. The solubility of this compound can be influenced by various factors including temperature and the polarity of the solvent utilized. Here are some key points to consider:

  • Polar and Nonpolar Solvents: Due to the presence of both an aromatic ring and an amino group, 2-(diethylamino)ethyl benzoate can exhibit variable solubility. It is typically more soluble in nonpolar solvents compared to polar solvents, largely because of its hydrophobic aromatic structure.
  • Temperature Dependence: As with many organic compounds, the solubility of 2-(diethylamino)ethyl benzoate tends to increase with a rise in temperature. This means that at elevated temperatures, the solute may dissolve more readily, making it important to consider during experimental procedures.
  • pH Influence: The solubility can also be affected by the pH of a solution. The basic amino group may interact with protons, affecting the overall solubility depending on the acidic or basic nature of the medium.

In summary, the solubility of 2-(diethylamino)ethyl benzoate is a combination of its molecular structure and environmental conditions. Understanding these aspects can greatly influence its applications in various chemical reactions and formulations. As the saying goes, "Like dissolves like," which highlights the importance of selecting appropriate solvents for optimal solubility.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl Benzoate

2-(Diethylamino)ethyl benzoate is a fascinating chemical compound with various applications, particularly in the field of organic chemistry and pharmaceuticals. Here are some noteworthy aspects:

  • Pharmaceutical Relevance: This compound is often used as an intermediate in the synthesis of various pharmaceuticals. Its structure allows for modifications that can lead to the development of new therapeutic agents.
  • Local Anesthetic Properties: Due to the presence of the diethylamino group, 2-(diethylamino)ethyl benzoate can exhibit local anesthetic effects. Compounds with similar structures have been known to block nerve conduction, making them useful in medical applications.
  • Unique Chemical Structure: The molecular framework of 2-(diethylamino)ethyl benzoate consists of an ester functional group and a tertiary amine. This feature imparts distinct reactivity, making it an interesting subject of study in organic synthesis.
  • Research Potential: The compound's ability to interact with biological systems and the potential to derive novel derivatives opens avenues for research in medicinal chemistry and drug design.
  • Safety Precautions: Like many nitrogen-containing compounds, safety measures must be taken when handling it. Proper ventilation and personal protective equipment (PPE) are essential due to its potential irritant effects.

With ongoing research into its applications and properties, 2-(diethylamino)ethyl benzoate continues to be a subject of interest in various scientific communities. As one researcher aptly put it, "the only limit to a compound's usefulness is our imagination!"

Synonyms
BENZOIC ACID, 2-(DIETHYLAMINO)ETHYL ESTER
2572-39-6
beta-Benzoyloxyethyl diethylamine
AI3-05644
BRN 1959437
DTXSID10180408
.beta.-Benzoyloxyethyl diethylamine
4-09-00-00561 (Beilstein Handbook Reference)
DTXCID80102899
gevphaftdxtzhy-uhfffaoysa-n
2-(Diethylamino)ethyl benzoate
2-diethylaminoethyl benzoate
XQV4S4W9G3
UNII-XQV4S4W9G3
SCHEMBL453815
2-(Diethylamino)ethyl benzoate #
2-(Diethylamino)ethyl benzoate HCl
Ethanol, 2-diethylamino-, benzoate
AE-641/04594033