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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(diethylamino)ethyl N-(1-naphthyl)carbamate
State
State

At room temperature, Procaine is a solid. It is typically supplied in its hydrochloride salt form, which is more stable and easily soluble in water for medical applications.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
370.00
Boiling point (Kelvin)
643.15
General information
Molecular weight
236.31g/mol
Molar mass
236.3130g/mol
Density
1.1000g/cm3
Appearence

Procaine appears as a white crystalline powder. It is typically odorless with a slightly bitter taste. Due to its structure, the compound is able to form salts that are water-soluble, often used in its hydrochloride form.

Comment on solubility

Solubility of 2-(Diethylamino)ethyl N-(1-naphthyl)carbamate

The solubility of 2-(diethylamino)ethyl N-(1-naphthyl)carbamate can be described as __moderate__ in various solvents. Understanding its solubility properties is essential for various applications including pharmaceuticals and chemistries. Here are some key points regarding its solubility:

  • Polar Solvents: This compound exhibits reasonable solubility in polar solvents due to the presence of the diethylamino and carbamate groups, which can engage in hydrogen bonding.
  • Non-Polar Solvents: Its solubility in non-polar solvents may be limited, reflecting the hydrophobic nature of the naphthalene ring present in its structure.
  • pH Sensitivity: The solubility can be influenced by the pH of the solution, as the ionization of the amino group can alter its interactions with water.
  • Temperature Dependence: Generally, an increase in temperature enhances solubility, allowing greater dissolution in solvents.

In practical applications, it is important to consider these characteristics of solubility in order to achieve optimal use of 2-(diethylamino)ethyl N-(1-naphthyl)carbamate within formulations. As a rule of thumb, the right solvent and conditions can significantly improve the compound's effectiveness in various chemical processes.

Interesting facts

Interesting Facts About 2-(diethylamino)ethyl N-(1-naphthyl)carbamate

2-(diethylamino)ethyl N-(1-naphthyl)carbamate is a fascinating chemical compound with several intriguing properties and applications. Here are some interesting facts about this compound:

  • Mechanism of Action: This compound acts primarily as a reversible inhibitor of acetylcholinesterase, which makes it a valuable research tool in neurochemistry. It plays a critical role in studying neurotransmission and the cholinergic system.
  • Pharmaceutical Applications: Given its properties, it has been explored in the development of drugs aimed at treating conditions such as Alzheimer's disease and myasthenia gravis. The inhibition of acetylcholinesterase can help in increasing the levels of acetylcholine, a key neurotransmitter, in the synaptic cleft.
  • Structure and Stability: The complexity of its structure, featuring the naphthalene ring, contributes to its chemical stability and interaction with biological systems. The presence of the diethylamino group enhances its solubility in organic solvents, making it advantageous for certain synthesis processes.
  • Synthesis: The synthesis of this compound typically involves a multi-step reaction that can highlight the importance of protecting groups and controlling reaction conditions to ensure yield and purity.
  • Safety Considerations: Like many organic compounds, precautions should be taken when handling this substance, as it may pose risks such as toxicity or skin irritation. Proper laboratory safety protocols are essential.

In summary, 2-(diethylamino)ethyl N-(1-naphthyl)carbamate serves not only as an essential component in the study of neurotransmitter dynamics but also holds potential for practical applications in medicine. Its ability to interact with various biological systems continues to make it a topic of interest among chemists and pharmacologists alike.

Synonyms
23379-39-7
2-(diethylamino)ethyl 1-naphthylcarbamate
DA-07868