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Clomethiazole

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Identification
Molecular formula
C13H19ClN2O2
CAS number
533-45-1
IUPAC name
2-(diethylamino)ethyl N-(3-chloro-2-methyl-phenyl)carbamate
State
State

Clomethiazole is typically in solid form at room temperature.

Melting point (Celsius)
85.00
Melting point (Kelvin)
358.15
Boiling point (Celsius)
295.00
Boiling point (Kelvin)
568.15
General information
Molecular weight
344.86g/mol
Molar mass
344.8550g/mol
Density
1.1000g/cm3
Appearence

Clomethiazole is typically presented as a powder or crystalline solid. It can appear as a white to off-white crystalline substance.

Comment on solubility

Solubility of 2-(diethylamino)ethyl N-(3-chloro-2-methyl-phenyl)carbamate

The solubility of the compound 2-(diethylamino)ethyl N-(3-chloro-2-methyl-phenyl)carbamate can be described as follows:

  • Solvent Interactions: The presence of both hydrophilic (diethylamino and carbamate) and hydrophobic (3-chloro-2-methyl-phenyl) groups allows for varied interactions with solvents.
  • Polarity: The overall polarity of the molecule significantly impacts its solubility in polar vs non-polar solvents.
  • Miscibility: The compound is likely to show better solubility in polar organic solvents such as methanol and ethanol due to its polar functional groups.
  • Temperature Effect: Temperature changes can modify the solubility, often increasing it in most solvents as temperature rises.
  • pH Dependence: Given the carbamate group, solubility may also vary with pH, as protonation can affect the solubility in aqueous solutions.

In summary, 2-(diethylamino)ethyl N-(3-chloro-2-methyl-phenyl)carbamate demonstrates complex solubility behaviors influenced by its structural features and the characteristics of the solvent used. The balance of polar and non-polar elements in this compound provides a versatile profile in varying solubility conditions.

Interesting facts

Interesting Facts about 2-(Diethylamino)ethyl N-(3-chloro-2-methyl-phenyl)carbamate

2-(Diethylamino)ethyl N-(3-chloro-2-methyl-phenyl)carbamate is a fascinating compound in the field of medicinal chemistry. It belongs to the class of carbamate compounds, which are known for their diverse applications, particularly in pharmaceuticals, agrochemicals, and synthetic chemistry.

Key Properties & Applications

  • Pharmaceutical Relevance: This compound is often explored for its potential use in developing medications. Carbamate derivatives can act as inhibitors for certain enzymes in the body, making them valuable in treating various medical conditions.
  • Agrochemical Insights: Compounds like this may have utility in agriculture, serving as pesticides or herbicides due to their ability to disrupt the nervous systems of pests.
  • Synthetic Versatility: The structural features of this carbamate compound allow for several synthetic pathways, enabling chemists to modify it to create new derivatives with potentially enhanced properties.

Unique Features

This compound exhibits unique characteristics due to its substitution patterns:

  • Diatomic Influence: The diethylamino group contributes to its lipophilicity, enabling easier cell membrane penetration.
  • Chloro-Methyl Phenyl Group: The presence of chlorine and a methyl group introduces interesting electronic effects that can influence the compound's biological activity.

Research Insights

Recent studies have shown that compounds like 2-(diethylamino)ethyl N-(3-chloro-2-methyl-phenyl)carbamate can have selective activity against specific enzymes, leading to targeted therapeutics with lower side effects compared to traditional drugs. A quote from recent research highlights its potential: "The selective inhibition of target enzymes presents an opportunity for more effective and safer treatment options."

Overall, this compound is more than just a chemical formula; it represents a bridge between synthetic innovation and practical applications in health and agriculture. The ongoing research into such compounds continues to reveal the intricate connections between chemistry and real-world solutions.