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2-(diisobutylamino)acetohydrazide

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Identification
Molecular formula
C8H19N3O
CAS number
274169-35-0
IUPAC name
2-(diisobutylamino)acetohydrazide
State
State

At room temperature, 2-(diisobutylamino)acetohydrazide is typically in a liquid state but can crystallize into a solid. Its physical state can vary depending on the specific conditions, including temperature and pressure.

Melting point (Celsius)
24.00
Melting point (Kelvin)
297.20
Boiling point (Celsius)
312.50
Boiling point (Kelvin)
585.70
General information
Molecular weight
201.32g/mol
Molar mass
201.3160g/mol
Density
1.0050g/cm3
Appearence

2-(Diisobutylamino)acetohydrazide typically appears as a colorless to pale yellow liquid or solid, depending on its purity and the ambient temperature. It is generally without a strong odor and may appear as a crystalline substance when solidified.

Comment on solubility

Solubility of 2-(diisobutylamino)acetohydrazide

The solubility of 2-(diisobutylamino)acetohydrazide is significant for its application in various chemical processes. Understanding its solubility behavior can be crucial for effective utilization in synthesis and formulation. Here are key points regarding its solubility:

  • Solvent Dependence: This compound exhibits varying solubility in different solvents, typically showing greater solubility in organic solvents due to its hydrophobic diisobutylamino groups.
  • Temperature Influence: As with many organic compounds, an increase in temperature generally leads to an increase in solubility. Therefore, higher temperatures may enhance its dissolution in suitable solvents.
  • Aqueous Solubility: The degree of solubility in water is limited, primarily due to the presence of large hydrophobic groups, which may hinder interaction with water molecules.
  • pH Sensitivity: The solubility may also be influenced by the pH of the solvent, particularly if protonation or deprotonation could occur under specific conditions.

In summary, while 2-(diisobutylamino)acetohydrazide tends to be more soluble in organic environments, its solubility profile is subject to variations influenced by solvent choice, temperature, and pH. Thus, when working with this compound, it is essential to consider these factors to ensure optimal performance in any applications.

Interesting facts

Interesting Facts about 2-(Diisobutylamino)acetohydrazide

2-(Diisobutylamino)acetohydrazide is a fascinating compound that has garnered attention in various fields of chemistry due to its unique properties and potential applications. Here are some noteworthy points:

  • Functionality: This compound is primarily recognized as a hydrazone derivative, which means it contains specific functional groups that can undergo various chemical reactions, making it an essential building block in organic synthesis.
  • Research Applications: It has been studied for its utility in biochemical applications, especially in drug development, where modifications to the hydrazide framework can enhance therapeutic efficacy.
  • Regulatory Interest: Compounds containing hydrazine derivatives are often scrutinized for their potential implications in medicinal chemistry, as hydrazines can exhibit toxicity and other health risks, necessitating careful study and handling.
  • Synthesis Insight: The synthesis of 2-(diisobutylamino)acetohydrazide typically involves a reaction between hydrazine derivatives and carbonyl compounds. This synthesis pathway is significant for those looking to design and manipulate organic compounds in a laboratory setting.

Researchers often emphasize the importance of understanding the reactivity and stability of similar compounds:

"Understanding the properties of hydrazone derivatives opens new avenues in drug discovery and synthesis." - A prominent researcher in organic chemistry

In conclusion, 2-(diisobutylamino)acetohydrazide serves as an intriguing compound in the realm of chemistry, showcasing the intricate connections between structure, reactivity, and application. Its multifaceted role makes it a compound worth studying for both budding chemists and seasoned researchers alike.

Synonyms
N,N-Diisobutylglycine hydrazide
2644-37-3
GLYCINE, N,N-DIISOBUTYL-, HYDRAZIDE
BRN 1210425
DTXSID50181035
DTXCID60103526
AKOS012894680