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Diisopropylethanolamine

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Identification
Molecular formula
C8H19NO
CAS number
96-80-0
IUPAC name
2-(diisopropylamino)ethanol
State
State

At room temperature, 2-(Diisopropylamino)ethanol is a liquid. It is relatively stable under standard conditions but will absorb water from the atmosphere due to its hygroscopic nature.

Melting point (Celsius)
-60.00
Melting point (Kelvin)
213.15
Boiling point (Celsius)
176.00
Boiling point (Kelvin)
449.15
General information
Molecular weight
131.24g/mol
Molar mass
131.2240g/mol
Density
0.8436g/cm3
Appearence

2-(Diisopropylamino)ethanol is typically a colorless liquid. It might appear slightly viscous at room temperature. The compound is hygroscopic, meaning it can absorb moisture from the air, which could slightly alter its appearance if exposed for extended periods.

Comment on solubility

Solubility of 2-(diisopropylamino)ethanol

2-(diisopropylamino)ethanol, with its unique molecular structure, exhibits interesting solubility characteristics. Here are some key points regarding its solubility:

  • Good Solubility in Polar Solvents: This compound is known to be soluble in polar solvents such as water and alcohols. The presence of hydroxyl (-OH) and amino groups supports strong hydrogen bonding with these solvents.
  • Limited Solubility in Non-polar Solvents: Conversely, its solubility in non-polar solvents is significantly lower due to a lack of favorable interactions. Typical non-polar solvents like hexane or benzene do not dissolve 2-(diisopropylamino)ethanol effectively.
  • Temperature Dependence: The solubility may also change with temperature. Generally, higher temperatures can enhance the solubility of organic compounds in solvents by increasing molecular motion.

In summary, while 2-(diisopropylamino)ethanol can dissolve well in polar environments, it struggles in non-polar conditions. This solubility behavior is crucial for its applications in chemical syntheses and biological systems, where solvent choice can significantly impact the overall reactivity and stability of the compound.

Interesting facts

Interesting Facts about 2-(Diisopropylamino)ethanol

2-(Diisopropylamino)ethanol is a fascinating compound that has garnered attention in various fields of chemistry and pharmacology. Here are some intriguing aspects of this chemical:

  • Functionality: This compound is classified as an amino alcohol, which means it contains both an amine and an alcohol functional group. This dual functionality allows it to engage in a wide range of reactions, making it highly versatile in synthetic chemistry.
  • Role in Synthesis: It is often used as a starting material or building block in the synthesis of more complex molecules, including pharmaceuticals and agrochemicals.
  • Potential Biological Activity: Compounds with similar structures have been shown to exhibit various biological activities, including effects on the central nervous system. The diisopropylamino group can influence how the molecule interacts with biological targets.
  • Solvent Properties: This compound has unique properties that can be advantageous as a solvent in various chemical reactions. Its ability to dissolve both polar and nonpolar substances makes it useful in diverse applications.
  • Research and Development: Due to its structural characteristics, 2-(diisopropylamino)ethanol is often a subject of research aimed at developing new drugs or enhancing existing therapies.

As noted by chemical researchers, “The design of amino alcohols is crucial in medicinal chemistry; their ability to interact with biological systems opens new pathways for drug innovation.”
This emphasizes the importance of compounds like 2-(diisopropylamino)ethanol in the broader context of chemical research and pharmaceutical development.

In summary, 2-(diisopropylamino)ethanol serves as a prime example of how a simple structural modification can lead to compounds with diverse functionalities and potential applications. Its ongoing study underscores the dynamic relationship between chemistry and real-world applications.

Synonyms
2-(Diisopropylamino)ethanol
96-80-0
2-Diisopropylaminoethanol
(Diisopropylamino)ethanol
Diisopropylethanolamine
N,N-Diisopropyl ethanolamine
N,N-Diisopropylethanolamine
N,N-Diisopropylaminoethanol
Ethanol, 2-[bis(1-methylethyl)amino]-
(N,N-Diisopropylamino)ethanol
Ethanol, 2-(diisopropylamino)-
2-(Diisopropylamino)ethyl alcohol
Diisopropyl ethanolamine
2-[di(propan-2-yl)amino]ethanol
NSC 45475
DK7FND4TJZ
Monoethanoldiisopropylamine
2-Diisopropylamino-ethanol
EINECS 202-536-2
BRN 1697955
DIPAE
Ethanol, 2-(bis(1-methylethyl)amino)-
AI3-26461
NSC-45475
2-[Bis(Propan-2-Yl)Amino]Ethan-1-Ol
DTXSID6021822
2-(N,N-diisopropylamino)ethanol
4-04-00-01504 (Beilstein Handbook Reference)
2-[bis(1-methylethyl)amino]ethanol
2-(BIS(1-METHYLETHYL)AMINO)ETHANOL
2-(dipropan-2-ylamino)ethanol
2-(di(propan-2-yl)amino)ethanol
Aminoalkohol
UNII-DK7FND4TJZ
(Diisopropylethanol)amine
Ethanol, diisopropylamino-
SCHEMBL35561
N,N-(Diisopropyl)ethanolamine
N,N-(Diisopropylethanol)amine
CHEMBL122184
DTXCID101822
ZYWUVGFIXPNBDL-UHFFFAOYSA-
NSC45475
Tox21_301869
WLN: Q2NY1&1&Y1&1
BBL010947
MFCD00008869
STK802048
Ethanol, 2-bis(1-methylethyl)amino-
2-(Diisopropylamino)ethanol, >=99%
AKOS005622713
N,N-DIISOPROPYL-2-AMINOETHANOL
FD38670
UN 2825
CAS-96-80-0
NCGC00255178-01
VS-02763
D1062
NS00040502
propane, 2-N-(2-hydroxyethyl)-N-isopropylamino-
Q6951322
N,N-Diisopropylethanolamine;N,N-Diisopropyl-(beta)-amino ethanol
InChI=1/C8H19NO/c1-7(2)9(5-6-10)8(3)4/h7-8,10H,5-6H2,1-4H3
[(2R,3S,5R)-5-(4-amino-2-oxo-pyrimidin-1-yl)-2-[[hydroxy-[hydroxy(phosphonooxy)phosphoryl]oxy-phosphoryl]oxymethyl]tetrahydrofuran-3-yl] phosphono hydrogen phosphate