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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(diisopropylamino)ethyl 4-aminobenzoate
State
State

Procaine is typically a solid at room temperature. It is commonly available as its hydrochloride salt, which is soluble in water, making it easier to use in medical applications, especially as a local anesthetic.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
426.00
Boiling point (Kelvin)
699.15
General information
Molecular weight
236.31g/mol
Molar mass
236.3070g/mol
Density
1.1230g/cm3
Appearence

Procaine appears as a white, crystalline solid or powder. It is typically odorless and has a slight bitter taste. As a pharmaceutical compound, it is often used as a hydrochloride salt, known as procaine hydrochloride, which is more stable and soluble.

Comment on solubility

Solubility of 2-(diisopropylamino)ethyl 4-aminobenzoate

The solubility of 2-(diisopropylamino)ethyl 4-aminobenzoate, a compound with both hydrophobic and hydrophilic regions, can be quite intriguing. Understanding its solubility characteristics is crucial for applications in various chemical environments. Here are some key points to consider:

  • Polar versus Nonpolar Solubility: This compound has a diisopropylamino group, making it less polar than typical amines. The presence of the 4-aminobenzoate moiety, however, introduces some polarity, influencing solubility in solvents.
  • Solvent Interactions: 2-(diisopropylamino)ethyl 4-aminobenzoate is likely to dissolve better in organic solvents such as ethanol or dichloromethane, while showing limited solubility in water.
  • Temperature Dependency: Like many organic compounds, the solubility of this compound may increase with temperature, allowing for a more favorable dissolution process in suitable solvents.

Overall, the solubility profile of 2-(diisopropylamino)ethyl 4-aminobenzoate highlights the balance between its hydrophobic and hydrophilic characteristics, pointing towards its functional versatility across different chemical settings.

Interesting facts

Interesting Facts about 2-(diisopropylamino)ethyl 4-aminobenzoate

2-(diisopropylamino)ethyl 4-aminobenzoate, often referred to as a member of the amino benzoate family, is notable for its diverse applications in the fields of pharmaceuticals and chemical research. Here are some intriguing points about this compound:

  • Pharmacological Properties: This compound is frequently studied for its potential use as a local anesthetic. It operates by inhibiting sodium channels, thereby blocking nerve conduction, which can help alleviate pain in medical procedures.
  • Structural Features: The presence of diisopropylamino groups contributes to its lipophilicity, which enhances its ability to penetrate cellular membranes. This structural characteristic can influence its effectiveness and distribution throughout the body.
  • Synthesis Insights: Creating this compound typically involves intricate synthetic pathways that may include the reaction of amino acids with various acylating agents. Understanding the synthesis of such compounds can lead to the development of new derivatives with even more optimized medicinal properties.
  • Research Potential: Ongoing studies are evaluating the compound's efficacy in treating conditions beyond pain relief, such as its role in managing anxiety disorders, given its central nervous system implications.
  • Safety and Toxicology: As a compound used in pharmacology, assessing the safety profile is critical. Investigations into the compound’s toxicity, side effects, and interactions with other drugs are crucial for ensuring therapeutic efficacy and patient safety.

In summary, 2-(diisopropylamino)ethyl 4-aminobenzoate is a compound of significant interest due to its pharmacological applications and the potential for further development in the medical and chemical fields. Its unique structure and properties open up various avenues for research and application.