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2-(Dimethylamino)-1-(1-ethyl-1H-indol-3-yl)ethanol

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Identification
Molecular formula
C14H20N2O
CAS number
88085-33-4
IUPAC name
2-(dimethylamino)-1-(1-ethylindol-3-yl)ethanol
State
State
This compound is typically found as a solid at room temperature, specifically existing in a crystalline or powdered form. It is stable under normal temperatures and pressures.
Melting point (Celsius)
116.00
Melting point (Kelvin)
389.15
Boiling point (Celsius)
345.00
Boiling point (Kelvin)
618.15
General information
Molecular weight
232.33g/mol
Molar mass
232.3330g/mol
Density
1.1710g/cm3
Appearence

This compound is typically seen as a crystalline solid in its pure form. It can appear as a powder or crystallize in different forms depending on the solvent used in crystallization. The color may range from white to off-white, or sometimes slightly yellowish, especially if impurities are present. No significant odor is associated with this compound.

Comment on solubility

Solubility of 2-(Dimethylamino)-1-(1-ethylindol-3-yl)ethanol

When it comes to the solubility of 2-(dimethylamino)-1-(1-ethylindol-3-yl)ethanol, there are several intriguing aspects to consider:

  • Polar Nature: The presence of the dimethylamino group creates a polar environment, which often enhances solubility in polar solvents such as water and alcohols.
  • Hydrophilic Interactions: The hydroxyl (-OH) group in the structure enables hydrogen bonding with water, which significantly contributes to its solubility profile.
  • Alkyl Chain Influence: The ethyl group is typically associated with moderate hydrophobicity, which can affect how well the compound dissolves in mixed solvent systems.

As a result, 2-(dimethylamino)-1-(1-ethylindol-3-yl)ethanol is expected to exhibit varying solubility in:

  1. Water: Likely to be soluble due to hydrogen bonding capabilities.
  2. Organic solvents: May show variable solubility based on the polarity of the solvent.

In summary, the solubility of this compound is influenced by its unique structure, with both polar and hydrophobic characteristics playing vital roles. Understanding these interactions is key to predicting dissolution behavior in various environments.

Interesting facts

Facts about 2-(dimethylamino)-1-(1-ethylindol-3-yl)ethanol

2-(dimethylamino)-1-(1-ethylindol-3-yl)ethanol is an intriguing compound within the realm of organic chemistry, particularly due to its notable applications and structural characteristics. Here are some captivating aspects of this compound:

  • Unique Structure: The compound features an indole ring, which is a bicyclic structure known for its role in various biological activities. Indole derivatives are often found in numerous natural products and pharmaceuticals.
  • Biological Significance: Compounds similar to 2-(dimethylamino)-1-(1-ethylindol-3-yl)ethanol have been studied for their effects on neurotransmitter systems. They show promise in areas such as neuropharmacology and could potentially aid in the development of new therapeutic agents for mood disorders.
  • Dimethylamino Group: The presence of the dimethylamino group enhances the compound's basicity and solubility in biological systems, making it a focal point for research in medicinal chemistry.
  • Research Potential: This compound is currently of interest in scientific studies aimed at understanding its mechanism of action, particularly regarding serotonin and dopamine receptors, which are critical in mood regulation.
  • Applications in Drug Development: The unique combination of the indole structure and the amino alcohol can lead to innovative approaches in designing synthetic drugs, potentially leading to breakthroughs in treating various neurological conditions.
  • Multifunctionality: Like many indole derivatives, this compound may exhibit multifunctional properties, which can enhance its efficacy as a drug candidate through target engagement.

As research continues, compounds like 2-(dimethylamino)-1-(1-ethylindol-3-yl)ethanol will undoubtedly play a crucial role in expanding our understanding of organic molecules and their interactions within biological systems. The exploration of such compounds not only contributes to basic scientific knowledge but also holds the key to novel therapeutic strategies.

Synonyms
NSC 9085
BRN 0192669
5135-83-1
alpha-((Dimethylamino)methyl)-1-ethylindole-3-methanol
INDOLE-3-METHANOL, alpha-((DIMETHYLAMINO)METHYL)-1-ETHYL-
4-22-00-05687 (Beilstein Handbook Reference)
NSC9085
DTXSID201031430
NSC-9085
2-(dimethylamino)-1-(1-ethyl-1H-indol-3-yl)ethanol
alpha-((Dimethylamino)methyl)-1-ethyl-indole-3-methanol