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DMPP

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Identification
Molecular formula
C11H17NO
CAS number
5805-02-9
IUPAC name
2-(dimethylamino)-1-phenyl-propan-1-ol
State
State

This compound is a liquid at room temperature.

Melting point (Celsius)
29.00
Melting point (Kelvin)
302.15
Boiling point (Celsius)
242.00
Boiling point (Kelvin)
515.15
General information
Molecular weight
179.27g/mol
Molar mass
179.2680g/mol
Density
1.0160g/cm3
Appearence

The compound 2-(dimethylamino)-1-phenyl-propan-1-ol typically appears as a colorless to pale yellow liquid with a characteristic odor.

Comment on solubility

Solubility of 2-(Dimethylamino)-1-phenyl-propan-1-ol (C11H17NO)

The solubility of 2-(dimethylamino)-1-phenyl-propan-1-ol is influenced by its unique structure and functional groups. As a tertiary amine, it exhibits properties that contribute to its **solubility** in various solvents. Here are some key factors to consider:

  • Polarity: The presence of the dimethylamino group enhances the compound's polarity, making it soluble in polar solvents such as water and alcohols.
  • Hydrogen Bonding: The hydroxyl group (-OH) may participate in hydrogen bonding, which can further enhance solubility in protic solvents.
  • Hydrophobic Interactions: The phenyl group introduces some hydrophobic characteristics, allowing for solubility in organic solvents like dichloromethane or ethyl acetate.

In general, 2-(dimethylamino)-1-phenyl-propan-1-ol is expected to be more soluble in polar solvents due to the combination of its hydrophilic and hydrophobic features, illustrating the importance of structure in solubility considerations. Various solvent interactions and concentrations can further affect its solubility under specific conditions.

Interesting facts

Interesting Facts about 2-(Dimethylamino)-1-phenyl-propan-1-ol

2-(Dimethylamino)-1-phenyl-propan-1-ol, often referred to in shorthand as DMAP, is an intriguing compound primarily recognized for its role in medicinal chemistry and the development of pharmaceuticals. This compound features unique structural attributes, making it an important subject of study:

  • Medicinal Applications: DMAP is known for its use as an intermediate in the synthesis of various therapeutic agents. Its ability to serve as a building block allows chemists to create diverse chemical entities that may have significant biological activity.
  • Mechanism of Action: The presence of the dimethylamino group provides notable nucleophilicity, which can enhance reaction rates in certain chemical processes. This feature is particularly valuable in organic synthesis, where rapid reaction times are often desired.
  • Research Interests: Thanks to its intriguing structure, DMAP has become a topic of continuous research. Studies often focus on its potential as a drug delivery agent and its efficiency in synthesizing other important molecules.
  • Historical Significance: The investigation of DMAP dates back to several decades, tying it to many key discoveries in organic chemistry. This compound has left its mark in the annals of chemical literature and has inspired numerous studies aimed at improving synthetic methods.

In conclusion, 2-(dimethylamino)-1-phenyl-propan-1-ol embodies the intersection of structure and function in medicinal chemistry. As research evolves, the importance of such compounds in developing new therapies and understanding chemical processes cannot be overstated. It serves as a powerful reminder of how intricate organic compounds can be harnessed to push the boundaries of science.

Synonyms
N-Methylephedrine
Methylephedrine
Methylephedrin
17605-71-9
2-(dimethylamino)-1-phenylpropan-1-ol
Methylephedrin [German]
1-Phenyl-2-dimethylaminopropanol
2-(Dimethylamino)-1-phenyl-1-propanol
(1R,2S)-(-)-N-Methylephedrine
BENZYL ALCOHOL, alpha-(1-(DIMETHYLAMINO)ETHYL)-
(-)-N-Methylephedrine
L-N-METHYLEPHEDRINE HYDROCHLORIDE, 99
(-)-methylephedrine
1201-56-5
DL-Methylephedrine hydrochloride
N-METHYLEPHEDRINE [MI]
n-methyl-ephedrine
(1Rs,2Rs)-2-dimethylamino-1-phenylpropan-1-ol
N,N-Dimethylnorephedrine
SCHEMBL99674
CHEMBL4792285
CHEBI:90046
DTXSID70859481
AAA55279
AKOS003382393
DB-050860
DB-051881
NS00080752
Benzyl alcohol, .alpha.-(1-(dimethylamino)ethyl)-
Erythro-alpha-[1-(dimethylamino)ethyl]benzyl alcohol
Q27162269
benzene, 1-(2-dimethylamino-1-hydroxy)ethyl-4-hydroxy-
N,N-Dimethylnorephedrine2-dimethylamino-1-phenylpropanol
Benzenemethanol, .alpha.-[1-(dimethylamino)ethyl]-, [R-(R*,S*)]-
N-Methylephedrine, its salts, optical isomers, and salts of optical isomers (N-Methylephedrine)