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Actazinoform

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Identification
Molecular formula
C11H12N2O2
CAS number
67442-74-2
IUPAC name
2-(dimethylamino)-5-phenyl-oxazol-4-one
State
State

At room temperature, 2-(dimethylamino)-5-phenyl-oxazol-4-one is in a solid state.

Melting point (Celsius)
151.00
Melting point (Kelvin)
424.00
Boiling point (Celsius)
382.70
Boiling point (Kelvin)
655.85
General information
Molecular weight
216.24g/mol
Molar mass
216.2380g/mol
Density
1.1760g/cm3
Appearence

2-(Dimethylamino)-5-phenyl-oxazol-4-one is typically a crystalline solid. It may appear as a white to off-white powder depending on its purity and formulation.

Comment on solubility

Solubility of 2-(dimethylamino)-5-phenyl-oxazol-4-one

The solubility of 2-(dimethylamino)-5-phenyl-oxazol-4-one is noteworthy for several reasons:

  • Solvent Dependence: This compound exhibits variable solubility depending upon the solvent used. It is more soluble in polar solvents, which can effectively disrupt intermolecular forces.
  • Temperature Sensitivity: As with many organic compounds, its solubility can increase with temperature, making it beneficial in reactions that require higher conditions.
  • pH Influence: The presence of the dimethylamino group means that the solubility can be affected by the pH of the solution. In more basic conditions, protonation can occur, leading to increased solubility.
  • Hydrophobic Interactions: Given that a significant part of the compound has hydrophobic characteristics due to the phenyl group, it becomes less soluble in non-polar solvents.

In conclusion, understanding the solubility of 2-(dimethylamino)-5-phenyl-oxazol-4-one is crucial for its practical applications in synthetic chemistry and pharmaceuticals, as solubility is a key factor that influences reaction rates, efficacy, and bioavailability. As it is often said in chemistry, "solubility is the window to the world of reactivity."

Interesting facts

Interesting Facts about 2-(dimethylamino)-5-phenyl-oxazol-4-one

2-(dimethylamino)-5-phenyl-oxazol-4-one, commonly referred to in scientific literature as a derivative of oxazole, is a fascinating compound with various applications and intriguing characteristics. Here are some interesting facts:

  • Diverse Applications: This compound has been widely employed in the field of medicinal chemistry. Its unique structure allows for significant biological activity, making it a valuable subject of study in drug development.
  • Fluorescence: One of the standout features of 2-(dimethylamino)-5-phenyl-oxazol-4-one is its ability to exhibit strong fluorescence. This property is particularly useful in biochemical assays and can help in visualizing cellular processes.
  • Heterocyclic Chemistry: As a member of the oxazole class, this compound showcases the diversity of heterocyclic compounds. Heterocycles are a crucial component of many natural products and synthetic drugs.
  • Synthetic Routes: Scientists have explored various synthetic pathways to create this compound, including multi-step reactions that highlight the intricacies of organic synthesis. This aspect is of particular interest to chemistry students learning about synthetic methodologies.
  • Research Opportunities: The study of 2-(dimethylamino)-5-phenyl-oxazol-4-one opens avenues for research, especially in understanding its interactions with biological systems. It serves as an excellent example of how modifications to a chemical structure can lead to altered activity.

In conclusion, 2-(dimethylamino)-5-phenyl-oxazol-4-one is not just a compound but a gateway to understanding complex chemical behavior and applications. Its multifaceted nature showcases the brilliance of organic chemistry and its potential for innovation in various scientific fields.

Synonyms
THOZALINONE
655-05-0
Tozalinone
Stimsen
2-(Dimethylamino)-5-phenyl-2-oxazolin-4-one
Thozalinone [USAN]
CL 39808
4(5H)-Oxazolone, 2-(dimethylamino)-5-phenyl-
Tozalinonum [INN-Latin]
Tozalinona [INN-Spanish]
Tozalinone [INN]
2-Oxazolin-4-one, 2-(dimethylamino)-5-phenyl-
NSC 170962
Tozalinone (INN)
NSC-170962
BRN 0882816
Thozalinone (USAN)
CL-39808
5-Phenyl-2-dimethylamino-2-oxazolin-4-one
THOZALINONE [MI]
5-Phenyl-2-(dimethylamino)-2-oxazolin-4-one
UNII-68X5932947
2-(Dimethylamino)-5-phenyl-1,3-oxazol-4(5H)-one
Dimethyl derivative of Pemoline
68X5932947
Tozalinonum (INN-Latin)
Tozalinona (INN-Spanish)
jjshyeckyldyar-uhfffaoysa-n
2-(Dimethylamino)-5-phenyloxazol-4(5H)-one
Tozalinona
2-(dimethylamino)-5-phenyl-1,3-oxazol-4-one
4(5H)-Oxazolone,2-(dimethylamino)-5-phenyl-
CL 39808; NSC 170962; Stimsen; Tozalinone
NSC170962
Tozalinonum
2-(dimethylamino)-5-phenyl-oxazol-4-one
SCHEMBL49183
CHEMBL2105457
DTXSID70862359
GLXC-06092
AAA65505
AKOS026024880
WLN: T5NV DO CHJ CR& EN1&1
AS-16921
2-dimethylamino-5-phenyl-2-oxazolin-4-on
HY-105856
CS-0026794
NS00114117
D06115
EN300-253731
Q7797089
Z1509560706
2-(dimethylamino)-5-phenyl-4,5-dihydro-1,3-oxazol-4-one