Skip to main content

Fosfomycin

ADVERTISEMENT
Identification
Molecular formula
C3H7NO4P
CAS number
23155-02-4
IUPAC name
2-(dimethylamino)-6-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]oxazole-4,5-diol
State
State

At room temperature, fosfomycin is a solid. It is stable under normal conditions but should be stored in a sealed container to prevent moisture absorption.

Melting point (Celsius)
95.00
Melting point (Kelvin)
368.00
Boiling point (Celsius)
364.00
Boiling point (Kelvin)
637.00
General information
Molecular weight
138.12g/mol
Molar mass
138.1150g/mol
Density
1.5047g/cm3
Appearence

Fosfomycin is typically found as a white to almost white crystalline powder. It is hygroscopic and tends to clump upon exposure to air and moisture. It is often used in the form of its salts, such as the tromethamine salt, which are more stable and easier to handle.

Comment on solubility

Solubility of 2-(dimethylamino)-6-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]oxazole-4,5-diol

The solubility of the compound 2-(dimethylamino)-6-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]oxazole-4,5-diol, with the chemical formula C3H7NO4P, can vary significantly depending on several factors. Here are key points to consider:

  • Polarity: This compound contains functional groups that contribute to its polarity, which can enhance its solubility in polar solvents, such as water.
  • Hydrogen Bonding: The presence of hydroxyl (-OH) groups allows for strong hydrogen bonding interactions, further increasing solubility in polar environments.
  • Solvent Interaction: Solubility may be improved in solvents such as alcohols or dimethyl sulfoxide (DMSO), which can stabilize the solute through dipole-dipole interactions.
  • pH Dependency: Given that this compound contains amine functionalities, its solubility could also be influenced by the pH of the solution, potentially leading to increased solubility in more acidic or basic environments.

In conclusion, understanding the solubility of this compound involves considering its structure, the solvent's nature, and environmental conditions, all of which play pivotal roles in its behavior in solution. Thus, one might say, "Solubility is a complex dance between structure and environment, where every component influences the outcome."

Interesting facts

Interesting Facts about 2-(dimethylamino)-6-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d]oxazole-4,5-diol

This intriguing compound, known for its complex structure and unique functional groups, opens up a fascinating window into the world of organic chemistry. Here are several notable points worth considering:

  • Structural Complexity: This compound features a cyclopenta[d]oxazole ring, demonstrating the diverse architectures that organic molecules can adopt. Its intricate arrangement of atoms challenges traditional bonding understanding.
  • Biological Relevance: Compounds with similar structures often exhibit significant biological activities. Studying such derivatives can lead to advancements in pharmaceuticals, especially in designing drugs that target specific biochemical pathways.
  • Dimethylamino Group: The presence of a dimethylamino group not only impacts the compound's basicity but also contributes to its solubility and interaction with biological systems, making it a crucial functional group in medicinal chemistry.
  • Hydroxymethyl Substitution: The hydroxymethyl group adds to the compound's versatility, offering opportunities for further chemical modification, which is a key strategy in drug design and development.
  • Synthetic Challenges: Due to its intricate structure, synthesizing this compound may present several challenges, pushing chemists to develop innovative synthetic techniques and methodologies.

As scientists continue to explore the properties and potential applications of such compounds, it reinforces the idea that even the most complex structures can yield valuable insights into chemical behavior and therapeutic possibilities. Studying this compound provides an excellent opportunity for students and researchers alike to deepen their understanding of organic synthesis and molecular interactions.

"The beauty of chemistry lies in its complexity." - Anonymous

Synonyms
2-(dimethylamino)-6-(hydroxymethyl)-4,5,6,6a-tetrahydro-3aH-cyclopenta[d][1,3]oxazole-4,5-diol