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Nitrofurazone

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Identification
Molecular formula
C6H6N4O4
CAS number
59-87-0
IUPAC name
2-(dimethylamino)-N-[(5-nitro-2-furyl)methyleneamino]acetamide
State
State

At room temperature, nitrofurazone is typically found as a solid. However, in applications, it is often utilized in liquid forms like gels or ointments due to its therapeutic uses.

Melting point (Celsius)
236.50
Melting point (Kelvin)
509.70
Boiling point (Celsius)
439.30
Boiling point (Kelvin)
712.50
General information
Molecular weight
225.14g/mol
Molar mass
225.1550g/mol
Density
1.4940g/cm3
Appearence

Nitrofurazone appears as a yellowish crystalline solid. It is often used in ointment form and presents as a yellowish gel when mixed with other substances for medical or veterinary applications.

Comment on solubility

Solubility of 2-(dimethylamino)-N-[(5-nitro-2-furyl)methyleneamino]acetamide

When examining the solubility of 2-(dimethylamino)-N-[(5-nitro-2-furyl)methyleneamino]acetamide, one must consider several factors that contribute to its behavior in various solvents. This compound contains both polar and nonpolar moieties, which can influence solubility in different environments. Here are some key points to consider:

  • Polarity: The presence of the dimethylamino group suggests that the compound may exhibit some polar characteristics, potentially enhancing solubility in polar solvents such as water.
  • Hydrogen Bonding: The ability to form hydrogen bonds due to the amide functional group might aid in solubility in polar solvents.
  • Solvent Choice: As a general guideline, this compound may be more soluble in organic solvents like ethanol or dimethyl sulfoxide (DMSO) compared to pure water.
  • Temperature Influence: Increased temperature may improve solubility, especially in organic solvents where kinetic energy helps to overcome intermolecular forces.

As with many chemical compounds, the specific conditions and the presence of other solutes can drastically influence solubility behaviors. It is essential to conduct experimental trials under controlled conditions for precise solubility data.

Interesting facts

Interesting Facts about 2-(Dimethylamino)-N-[(5-nitro-2-furyl)methyleneamino]acetamide

This unique compound, often referred to in scientific literature, showcases the fascinating interplay between organic chemistry and medicinal applications. Its complex structure presents a variety of functional groups, making it an intriguing subject of study:

  • Functional Diversity: The compound contains a dimethylamino group, which is known for enhancing biological activity, particularly in pharmaceutical contexts.
  • Furyl Moiety: The presence of a nitro-substituted furan ring expands its potential applications as the furan derivatives are often linked to various bioactive compounds.
  • Potential Antimicrobial Properties: Many compounds resembling this structure have been studied for their antimicrobial effectiveness, suggesting that this molecule may possess similar characteristics.
  • Synthetic Utility: Its distinct arrangement of atoms allows for various synthetic pathways, making it a useful intermediate in organic synthesis.
  • Research Interest: This compound is often a topic of interest in drug design and development, leading to ongoing research focused on its pharmacological properties.

In chemistry, the synthesis and manipulation of such compounds often lead to discoveries of new materials or derivatives with enhanced functionality. As noted by many researchers, "The exploration of complex organic molecules continually reveals novel pathways for innovation." This goes to show how, even within the realm of a single compound, the possibilities for research and application can be both vast and impactful.

Furthermore, examining this compound provides insights into the broader field of medicinal chemistry, where understanding structure-activity relationships is crucial for developing effective therapeutics. Analysis of its activity and interactions can hint at potential roles in novel treatments, underscoring the importance of such detailed chemical studies.