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Naproxen

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Identification
Molecular formula
C14H14O3
CAS number
22204-53-1
IUPAC name
2-(dimethylamino)ethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate
State
State

Naproxen is typically found in a solid state at room temperature. It is commonly used in tablet form for medicinal purposes.

Melting point (Celsius)
153.00
Melting point (Kelvin)
426.15
Boiling point (Celsius)
386.00
Boiling point (Kelvin)
659.15
General information
Molecular weight
230.26g/mol
Molar mass
230.2590g/mol
Density
1.2160g/cm3
Appearence

The pure drug appears as a white to off-white crystalline powder.

Comment on solubility

Solubility of 2-(dimethylamino)ethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate

The solubility of 2-(dimethylamino)ethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate can be influenced by various factors, primarily due to its complex structure. Solubility characteristics can be categorized based on environmental conditions such as:

  • Polarity: The presence of both polar and nonpolar functional groups may result in moderate solubility in polar solvents like water.
  • Temperature: An increase in temperature typically enhances solubility for most organic compounds.
  • pH Levels: The ionization of the dimethylamino group may affect solubility in aqueous solutions, especially under varying pH conditions.

Generally, compounds incorporating naphthyl groups exhibit low to moderate solubility in water due to their hydrophobic nature. However, they may dissolve better in organic solvents, such as:

  • Dimethyl sulfoxide (DMSO)
  • Ethanol
  • Chloroform

In summary, while the solubility of 2-(dimethylamino)ethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate can be challenging to predict without empirical data, it is likely to display varied solubility depending on the surrounding conditions and solvents used. Understanding these interactions can assist in the effective application of this compound in various fields.

Interesting facts

Interesting Facts about 2-(Dimethylamino)ethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate

2-(Dimethylamino)ethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate is a fascinating compound with several notable characteristics and applications in the field of chemistry and pharmacology. Here are some key points to consider:

  • Unique Structure: This compound features a complex structure, which includes a tetrahydrofuran ring, a dimethylamino group, and a naphthalene moiety. Such structural diversity often leads to intriguing biochemical properties.
  • Potential Applications: Compounds containing similar structures are often explored for their potential therapeutic effects. They may show promise in areas like neurology or psychiatry, potentially acting as modulators for various neurotransmitter systems.
  • Development of New Drugs: Due to its unique functional groups, this compound could serve as a lead compound for the design of new medications, specifically those targeting brain chemistry.
  • Research Interest: Scientists continuously investigate compounds of this nature for their action mechanisms, metabolic pathways, and efficacy in treating mental health disorders, which remain crucial in contemporary pharmacological research.

In summary, 2-(dimethylamino)ethyl 2-(1-naphthylmethyl)-3-tetrahydrofuran-2-yl-propanoate illustrates the complexity and potential of organic compounds in medicinal chemistry. The ongoing exploration of such compounds may unveil new therapeutic avenues, making it a significant subject of study.