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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(dimethylamino)ethyl 2-(2-phenylethyl)benzoate
State
State

At room temperature, Lidocaine is typically a solid in the form of a white crystalline powder. However, it is most commonly used in a liquid form as part of a solution for injection or topical application in medical contexts.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.20
Boiling point (Celsius)
350.80
Boiling point (Kelvin)
624.00
General information
Molecular weight
234.34g/mol
Molar mass
234.3360g/mol
Density
1.0260g/cm3
Appearence

Lidocaine is typically available as a white crystalline powder. However, it is also commonly encountered in a solution form, especially in medical settings, where it is used for its anesthetic properties. The crystal structure suggests it has no odor, is highly soluble in water, and can be dissolved in alcohol, chloroform, and ether.

Comment on solubility

Solubility of 2-(dimethylamino)ethyl 2-(2-phenylethyl)benzoate

The solubility of 2-(dimethylamino)ethyl 2-(2-phenylethyl)benzoate can be quite complex due to its unique structure and functional groups. Understanding the factors that influence its solubility can provide valuable insights into its behavior in various environments.

Factors Affecting Solubility

  • Polarity: The compound contains both polar and non-polar functional groups, which affects its overall polarity. The presence of the -N(CH3)2 (dimethylamino) group enhances its solubility in polar solvents.
  • Solvent Type: This compound is likely to be more soluble in organic solvents such as ethanol or methanol compared to water due to the hydrophobic nature of its phenyl groups.
  • Temperature: As with most compounds, solubility generally increases with temperature, potentially making it more soluble in warmer solvents.

It is essential to note that while many organic compounds exhibit variable solubility, a rule of thumb is “like dissolves like.” Therefore, 2-(dimethylamino)ethyl 2-(2-phenylethyl)benzoate may find better solubility in environments that are similar to its chemical nature.

In summary, the solubility characteristics of this compound are multifaceted, influenced by factors such as polarity, solvent type, and temperature. These insights can aid in practical applications and experimental design.

Interesting facts

Interesting Facts about 2-(dimethylamino)ethyl 2-(2-phenylethyl)benzoate

The compound 2-(dimethylamino)ethyl 2-(2-phenylethyl)benzoate, commonly known for its applications in medicinal chemistry, exhibits a fascinating profile that captures the interest of both chemists and pharmacologists alike.

Key Features

  • Structure and Functionality: This compound features a complex structure with both amine and ester functionalities. The presence of the dimethylamino group significantly enhances its polar and basic character, which can influence its biological activity.
  • Potential Pharmacological Applications: Research suggests that derivatives of this compound may exhibit various pharmacological properties, including analgesic and anti-inflammatory effects. These possibilities make it an intriguing subject of study for drug development.
  • Versatility: The versatility of the phenylethyl moiety opens doors for modifications, enabling the design of analogs that may have tailored therapeutic effects or reduced side effects.

Research Significance

In the realm of medicinal chemistry, compounds like 2-(dimethylamino)ethyl 2-(2-phenylethyl)benzoate play a crucial role. They exemplify how slight modifications in molecular structure can lead to completely different biological outcomes. As the renowned chemist Linus Pauling once stated, “The best way to have a good idea is to have lots of ideas.” This statement rings true, as exploring variations of this compound could lead to novel drugs with profound impacts on health care.

Conclusion

In summary, 2-(dimethylamino)ethyl 2-(2-phenylethyl)benzoate represents a potent chemical structure worthy of extensive exploration. Its intriguing properties and potential applications highlight the importance of chemical research in the advancement of science and therapeutic solutions.