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Identification
Molecular formula
C12H16ClNO3
CAS number
78-44-4
IUPAC name
2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate
State
State

At room temperature, this compound is typically found in a solid state. Its form can be finely granulated or appear as larger crystallized chunks. Due to its crystalline structure, it usually maintains its form up to its melting point, which provides versatility in handling in both industrial and laboratory settings.

Melting point (Celsius)
98.30
Melting point (Kelvin)
371.50
Boiling point (Celsius)
315.70
Boiling point (Kelvin)
588.90
General information
Molecular weight
238.71g/mol
Molar mass
238.7100g/mol
Density
1.2074g/cm3
Appearence

2-(Dimethylamino)ethyl 2-(4-chlorophenoxy)acetate typically appears as a white to off-white crystalline powder. It is known for its characteristic form and is often used in various formulations and compounds where its structure plays a functional role. The crystalline nature of the compound is evident when observed under magnification, showcasing finely-formed crystals that can vary in size based on environmental conditions.

Comment on solubility

Solubility of 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate

The solubility of 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate (C12H16ClNO3) is an intriguing aspect of its chemical properties. This compound, with its unique structure, exhibits certain solubility characteristics that can be summarized as follows:

  • Polar and Non-Polar Interactions: Due to the presence of the dimethylamino group, which is polar, and the phenoxy group, which introduces a certain level of aromaticity, this compound may show variable solubility in different solvents.
  • Water Solubility: The solubility in water can be considered low to moderate because the bulky aromatic moiety may hinder effective hydrogen bonding despite the polar dimethylamino group.
  • Organic Solvents: It is expected to have better solubility in organic solvents such as ethanol, acetone, or dimethyl sulfoxide (DMSO) owing to its hydrophobic character from the aromatic ring.

As a property dictated by both molecular structure and environmental conditions, the solubility of this compound highlights the balance between hydrophilic and hydrophobic interactions within its molecular framework. Understanding this balance is crucial for applications in pharmaceuticals and agrochemicals, where solubility greatly influences bioavailability and efficacy.

Interesting facts

Exploring 2-(Dimethylamino)ethyl 2-(4-chlorophenoxy)acetate

2-(Dimethylamino)ethyl 2-(4-chlorophenoxy)acetate, often referred to in the scientific community with its abbreviated name, is a fascinating compound with a variety of applications and properties. Here are some interesting facts about this intriguing chemical:

  • Pharmaceutical Potential: This compound has garnered attention in drug development and medicinal chemistry. Its structure suggests it could play a role in the synthesis of various therapeutic agents.
  • Agricultural Uses: Compounds similar to 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate are often explored for their efficacy as herbicides or pesticide formulations, making them important in agriculture for pest management.
  • Structure-Activity Relationship: The presence of both a dimethylamino group and a phenoxyacetate moiety allows scientists to manipulate one of the functionalities to enhance the biological activity or reduce toxicity, providing a rich field for research.
  • Reactivity: This compound can participate in various chemical reactions including substitutions and couplings, making it a valuable intermediate in organic synthesis.
  • Research Applications: Due to its unique properties, it is often used as a building block in the design of complex organic molecules, serving as a key component in studies concerning chemical reactivity and interaction mechanisms.

In sum, 2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate is not merely a chemical formula; it serves as a portal into diverse research avenues, combining elements of medicinal chemistry, agricultural science, and synthetic organic chemistry. As scientists continue to unravel its potential, this compound exemplifies the vibrant interplay between structure, reactivity, and application in the world of chemistry.

Synonyms
meclofenoxate
Proseryl
Clofenoxin
Clophenoxate
Cetrexin
Analux
51-68-3
Deanolestere
Meclofenoxane
Meclophenoxate
Clopenoxin
Licidril
Mucidril
Cerebon
Centrexin
Centrophenoxine
Meclofenoxato
Mechlorphenoxatum
Deanol p-chlorophenoxyacetate
Clocete
Meclofenossato
Meclofenoxatum
Acephene
ANP 235
Meclofenossato [DCIT]
EN 1627
Meclofenoxatum [INN-Latin]
Meclofenoxato [INN-Spanish]
2-(dimethylamino)ethyl 2-(4-chlorophenoxy)acetate
Lucidryl
Luncidril
Meclofenoxate [INN:BAN:DCF]
NSC 169411
2-(Dimethylamino)ethyl (p-chlorophenoxy)acetate
UNII-C76QQ2I0RG
EINECS 200-116-3
C76QQ2I0RG
NSC-169411
Brenal (Salt/Mix)
BRN 1914094
Dimethylaminoethyl-p-chlorophenoxyacetate
Meclofenoxate (INN)
Atsephen (Salt/Mix)
Lucidril (Salt/Mix)
Lutiaron (Salt/Mix)
Helfergin (Salt/Mix)
Marucotol (Salt/Mix)
Proserout (Salt/Mix)
ANP-235
At sefen (Salt/Mix)
Dimethylaminoethyl-4-chlorophenoxyacetic acid
2-(Dimethylamino)ethyl(p-chlorphenoxy)acetate
Centrofenoxin (Salt/Mix)
MECLOFENOXATE [MI]
Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester
MECLOFENOXATE [INN]
Centrophenoxine (Salt/Mix)
dimethylaminoethyl p-chlorophenoxyacetate
p-Chlorophenoxyacetic acid beta-dimethylaminoethyl ester
NSC 4268 (Salt/Mix)
MECLOFENOXATE [WHO-DD]
CHEBI:6712
DTXSID9046940
2-(Dimethylamino)ethyl (p-chlorphenoxy)acetate
ACETIC ACID, (p-CHLOROPHENOXY)-, 2-(DIMETHYLAMINO)ETHYL ESTER
NSC169411
Meclofenoxate hydrochloride (Salt/Mix)
(4-Chlorophenoxy)acetic acid 2-(dimethylamino)ethyl ester
(p-Chlorophenoxy)acetic acid 2-(dimethylamino)ethyl ester
Analux; CPH; Cerebon; Cetrexin; Clocete
(p-Chlorophenoxy)acetic acid .beta.-(dimethylamino)ethyl ester
2-(Dimethylamino)ethyl p-chlorophenoxyacetate
2-(Dimethylamino)ethyl-4-(chlorophenoxy)acetate
Meclofenoxatum (INN-Latin)
Meclofenoxato (INN-Spanish)
Acetic acid, 2-(4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester
NCGC00015279-02
CAS-3685-84-5
Centrofenoxina
Centrophenoxin
Atsephen
At sefen
Spectrum_001569
Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester, hydrochloride
Prestwick0_000763
Prestwick1_000763
Prestwick2_000763
Prestwick3_000763
Spectrum2_000458
Spectrum4_000837
Spectrum5_001416
Lopac-C-8773
2-dimethylaminoethyl 2-(4-chlorophenoxy)acetate
Lopac0_000250
BSPBio_000806
KBioGR_001413
KBioSS_002049
CHEMBL64545
DivK1c_000367
SCHEMBL147339
SPBio_000536
SPBio_002745
BPBio1_000888
DTXCID7026940
KBio1_000367
KBio2_002049
KBio2_004617
KBio2_007185
WLN: GR DO1VO2N1&1
N06BX01
NINDS_000367
HY-17555A
STK182908
AKOS003657007
CCG-204345
DB13758
SDCCGSBI-0050238.P004
IDI1_000367
NCGC00015279-01
NCGC00015279-03
NCGC00015279-04
NCGC00015279-05
NCGC00015279-15
NCGC00162104-01
NCI60_000303
(Dimethylamino)ethyl p-chlorophenoxyacetate
SBI-0050238.P003
AB00053655
CS-0013660
NS00007464
EN300-57783
C08195
D00993
2-(Dimethylamino)ethyl (4-chlorophenoxy)acetate
AB00053655_09
(Dimethylamino)ethyl-4-(chlorophenoxy)acetic acid
2-(Dimethylamino)ethyl (4-chlorophenoxy)acetate #
Q421147
BRD-K10314788-003-04-4
BRD-K10314788-003-07-7
BRD-K10314788-003-12-7
p-Chlorophenoxy acetic acid 2-(dimethylamino)ethyl ester
(p-Chlorophenoxy)acetic acid beta-(dimethylamino)ethyl ester
Acetic acid, (4-chlorophenoxy)-, 2-(dimethylamino)ethyl ester, hydrochloride (9CI)
200-116-3