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Dexmedetomidine

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Identification
Molecular formula
C13H16N2
CAS number
145108-58-3
IUPAC name
2-(dimethylamino)ethyl 2-[(6S)-6-acetoxydecalin-2-ylidene]acetate
State
State

Dexmedetomidine is typically in a solid state at room temperature. It is often used in its hydrochloride form, which is crystalline.

Melting point (Celsius)
163.50
Melting point (Kelvin)
436.65
Boiling point (Celsius)
338.50
Boiling point (Kelvin)
611.65
General information
Molecular weight
236.19g/mol
Molar mass
236.1870g/mol
Density
0.9681g/cm3
Appearence

Dexmedetomidine hydrochloride appears as a white to off-white crystalline solid. It is highly soluble in water and soluble in organic solvents like methanol.

Comment on solubility

Solubility of 2-(dimethylamino)ethyl 2-[(6S)-6-acetoxydecalin-2-ylidene]acetate

The solubility of 2-(dimethylamino)ethyl 2-[(6S)-6-acetoxydecalin-2-ylidene]acetate can be influenced by a variety of factors, including its molecular structure and interactions with solvents. This compound contains both hydrophilic and hydrophobic features, which can have significant implications for its solubility.

Key Considerations for Solubility

  • Polar groups: The presence of the dimethylamino group enhances the compound's solubility in polar solvents due to its ability to engage in hydrogen bonding.
  • Hydrophobic regions: Conversely, the decalin structure provides a hydrophobic character, which can limit solubility in water.
  • Solvent choice: This compound is expected to dissolve well in organic solvents such as ethanol, methanol, and acetone while showing limited solubility in water.
  • Temperature effects: As with many organic compounds, increased temperature can enhance solubility in a given solvent.

In summary, the solubility of 2-(dimethylamino)ethyl 2-[(6S)-6-acetoxydecalin-2-ylidene]acetate is a complex interplay between its structural components and the solvent environment. Understanding these factors is crucial for practical applications and further studies.

Interesting facts

Interesting Facts about 2-(Dimethylamino)ethyl 2-[(6S)-6-acetoxydecalin-2-ylidene]acetate

This compound, known for its complex structure and potential applications, has captivated the interest of chemists and pharmacologists alike. Here are some fascinating insights about this molecule:

  • Structural Diversity: The presence of a dimethylamino group contributes to its unique properties, potentially influencing its biological activity and pharmacodynamics.
  • Stereochemistry: The "6S" designation in the name denotes a specific stereochemistry. Stereoisomers can have dramatically different properties and effects in biological systems, highlighting the importance of chirality in drug design.
  • Potential Applications: Compounds with acyl and amine functionalities are often investigated for their efficacy as pharmaceuticals. This molecule's intricate structure may provide lead compounds for treating various conditions.
  • Research Significance: The exploration of such compounds can lead to breakthroughs in medicinal chemistry and drug development, as researchers seek to optimize their therapeutic profiles.
  • Interdisciplinary Connections: Understanding and synthesizing this compound involves diverse fields of study, including organic chemistry, pharmacology, and medicinal chemistry, showcasing the interplay of different scientific disciplines.

As chemists continue to investigate the mechanisms of action and interactions of complex compounds like 2-(dimethylamino)ethyl 2-[(6S)-6-acetoxydecalin-2-ylidene]acetate, we may uncover novel therapeutic pathways that can significantly impact healthcare.