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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-(dimethylamino)ethyl 2,2-diphenylacetate
State
State

At room temperature, lidocaine is a solid.

Melting point (Celsius)
68.00
Melting point (Kelvin)
341.00
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.00
General information
Molecular weight
264.36g/mol
Molar mass
264.3630g/mol
Density
1.0261g/cm3
Appearence

Lidocaine typically appears as a white to slightly yellow crystalline powder. It is soluble in water and alcohol, providing flexibility for various pharmaceutical formulations.

Comment on solubility

Solubility of 2-(dimethylamino)ethyl 2,2-diphenylacetate

The solubility of 2-(dimethylamino)ethyl 2,2-diphenylacetate is influenced by its unique molecular structure, which combines both hydrophobic and hydrophilic characteristics. Understanding its solubility can be key to its application in various fields.

Factors Affecting Solubility:

  • Molecular Polarity: The presence of the dimethylamino group promotes some degree of polar character, potentially enhancing solubility in polar solvents.
  • Hydrophobic Nature: The diphenylacetate portion contributes to hydrophobic properties, which may limit solubility in water.
  • Temperature: Solubility can increase with temperature, as is typical for many organic compounds.
  • Solvent Choice: This compound may be more soluble in organic solvents such as ethanol or acetone compared to water.

In summary, while 2-(dimethylamino)ethyl 2,2-diphenylacetate displays some solubility characteristics based on its functional groups, it is essential to test specific conditions for its solubility in various solvents. As with many organic compounds, the balance between hydrophobic and hydrophilic interactions will dictate its overall solubility profile.

Interesting facts

Interesting Facts about 2-(Dimethylamino)ethyl 2,2-diphenylacetate

2-(Dimethylamino)ethyl 2,2-diphenylacetate, also known as Diphenylacetate, is a fascinating compound that captures the attention of chemists and researchers alike due to its unique structural characteristics and potential applications. Here are some intriguing facts about this compound:

  • Dual Functionality: The compound features a dimethylamino group that can act as a nucleophile, allowing it to participate in various chemical reactions, while the diphenylacetate moiety provides the structure with significant stability and electronic properties.
  • Pharmaceutical Relevance: This compound has garnered interest in the pharmaceutical industry, particularly in the development of drugs targeting neurological disorders due to the presence of the dimethylamino group, which may contribute to enhancing bioavailability.
  • Drug Synthesis: The synthesis of 2-(dimethylamino)ethyl 2,2-diphenylacetate exemplifies the beautiful complexity of organic synthesis, often involving several steps, such as esterification and amidation, which highlight the versatile synthetic pathways available in organic chemistry.
  • Research Potential: Ongoing studies investigate the structure-activity relationship (SAR) of compounds like this one, aiming to optimize their biological activity and minimize side effects, showcasing the importance of structure and reactivity in designing effective pharmaceuticals.
  • Mechanistic Insights: Understanding the mechanisms behind the reactions involving this compound can provide insights into how similar molecules behave, leveraging quantum chemistry and computational studies to predict outcomes in real-world applications.

In summary, 2-(dimethylamino)ethyl 2,2-diphenylacetate is much more than just a name; it embodies years of research, a wealth of knowledge, and endless possibilities for future exploration in the realms of chemistry and pharmacology. As one researcher aptly puts it, "Every molecule tells a story, waiting to be discovered."

Synonyms
2618-50-0
ACETIC ACID, DIPHENYL-, 2-(DIMETHYLAMINO)ETHYL ESTER
BRN 1985803
Diphenylacetic acid 2-(dimethylamino)ethyl ester
Benzeneacetic acid, alpha-phenyl-, 2-(dimethylamino)ethyl ester
DTXSID70180803
DTXCID70103294
2-(dimethylamino)ethyl diphenylacetate
Oprea1_317523
STK110358
AKOS003658411
EU-0001319
2,2-diphenyl-acetic acid-2-(dimethylamino)ethyl ester