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Procaine

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Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(dimethylamino)ethyl 4-aminobenzoate
State
State
Procaine is typically found as a solid at room temperature. Its form as either a crystalline powder or crystalline solid is stable under normal conditions, making it suitable for storage and use in pharmaceutical formulations.
Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
396.15
Boiling point (Kelvin)
669.30
General information
Molecular weight
236.31g/mol
Molar mass
236.3060g/mol
Density
1.1000g/cm3
Appearence

Procaine appears as a white, crystalline powder. It is odorless and has a slightly bitter taste. This compound is typically used in a finely powdered form or as a crystalline solid for various applications.

Comment on solubility

Solubility of 2-(dimethylamino)ethyl 4-aminobenzoate (C13H20N2O2)

The solubility of 2-(dimethylamino)ethyl 4-aminobenzoate, also known as DMAB, can be assessed based on its chemical structure and functional groups. As an organic compound with both amine and ester functionalities, it exhibits certain solubility characteristics:

  • Polar Functional Groups: The presence of the amine (-NH2) and ester (-COOR) groups contributes to its polar nature, enhancing solubility in polar solvents such as water and dimethyl sulfoxide (DMSO).
  • Hydrophobic Aromatic Structure: The benzene ring in its structure provides hydrophobic characteristics, which may hinder water solubility to some extent, yet allows it to dissolve well in organic solvents like ethanol and methanol.
  • pH Influence: The solubility may vary with changes in pH due to protonation of the amine group, which enhances its aqueous solubility in acidic conditions.

In a general sense, 2-(dimethylamino)ethyl 4-aminobenzoate is expected to have moderate solubility in water and higher solubility in organic solvents. Its solubility profile makes it suitable for various applications, particularly in pharmaceuticals and chemical synthesis.

Interesting facts

Interesting Facts About 2-(Dimethylamino)ethyl 4-aminobenzoate

2-(Dimethylamino)ethyl 4-aminobenzoate, commonly known in pharmaceutical and chemical circles for its unique properties, is a fascinating compound with numerous applications:

  • Pharmaceutical Applications: This compound is often utilized in the synthesis of local anesthetics and has gained attention for its role in blocking pain receptors.
  • Research Utility: Scientists explore its efficacy in various formulations, studying its interaction with biological systems and how it can enhance drug delivery.
  • Functional Group Diversity: Featuring both amino and ester functional groups, it exemplifies how such diversity can contribute to the versatility of compounds in medicinal chemistry.
  • Structural Insights: The presence of the dimethylamino group offers interesting polarization effects, which can influence its reactivity and interaction profiles.

The integration of amine functionalities often leads to unique pathways in synthetic organic chemistry, making compounds like this one essential in the development of new materials and pharmaceuticals. Notably, when discussing its origin, it can be informative to note that the synthesis pathways of such compounds can reveal much about the underlying principles of chemical behavior.

As an intriguing quote in the field suggests, “Chemistry is not about what you can see, but what you can imagine.” This statement holds particularly true when contemplating compounds like 2-(dimethylamino)ethyl 4-aminobenzoate, as their full potential is often unlocked through innovative research and experimentation.

Synonyms
Dimethylprocaine
10012-47-2
(Dimethylamino)ethyl p-aminobenzoate
2-(dimethylamino)ethyl 4-aminobenzoate
Benzoic acid, 4-amino-, 2-(dimethylamino)ethyl ester
NSC25247
NSC-25247
4-Aminobenzoic acid 2-(dimethylamino)ethyl ester
NSC 25247
BRN 2806149
BENZOIC ACID, p-AMINO-, 2-(DIMETHYLAMINO)ETHYL ESTER
Ethanol, 2-dimethylamino-, p-aminobenzoate
NCIStruc1_000570
NCIStruc2_000443
2-14-00-00251 (Beilstein Handbook Reference)
CHEMBL611747
SCHEMBL4835480
DTXSID30142967
NCI25247
CCG-37984
NCGC00013316
AKOS010576408
NCGC00013316-02
NCGC00096433-01
NCI60_002026
DS-007128
Benzoic acid, 4-amino-,2-(dimethylamino)ethyl ester