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2-[(Dimethylamino)methyl]phenol

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Identification
Molecular formula
C9H13NO
CAS number
33362-73-1
IUPAC name
2-[(dimethylamino)methyl]phenol
State
State

At room temperature, 2-[(dimethylamino)methyl]phenol is typically found in its liquid form. Its solid form appears as pale yellow crystals if at lower temperatures or in pure crystalline form.

Melting point (Celsius)
25.50
Melting point (Kelvin)
298.70
Boiling point (Celsius)
260.50
Boiling point (Kelvin)
533.70
General information
Molecular weight
151.21g/mol
Molar mass
151.2110g/mol
Density
0.9960g/cm3
Appearence

2-[(Dimethylamino)methyl]phenol is a pale yellow to yellow liquid at room temperature. It may also be found as a crystalline solid under certain circumstances, but is most commonly encountered in a liquid state due to its utility in various chemical reactions and as an intermediate in organic synthesis.

Comment on solubility

Solubility of 2-[(dimethylamino)methyl]phenol

2-[(dimethylamino)methyl]phenol, also known as 2-(N,N-dimethylaminomethyl)phenol, presents interesting solubility characteristics due to its structural features. Being a phenolic compound, it showcases some unique behavior in various solvents:

  • Solubility in water: This compound has moderate solubility in water. The presence of the dimethylamino group contributes to its polar nature, allowing for some degree of interaction with water molecules.
  • Solubility in organic solvents: 2-[(dimethylamino)methyl]phenol is highly soluble in organic solvents such as:
    • Ethyl alcohol
    • Acetone
    • Toluene
  • Temperature effect: The solubility can increase with temperature, making it advantageous for applications requiring higher solubility rates.
  • pH influence: The solubility in water can also be influenced by the pH of the solution, as the protonation state of the amino group may alter its interaction with water.

In summary, the solubility profile of 2-[(dimethylamino)methyl]phenol is significantly affected by both its molecular structure and the solvents used. The interplay between its polar and non-polar regions makes it versatile in various chemical environments.

Interesting facts

Interesting Facts about 2-[(dimethylamino)methyl]phenol

2-[(dimethylamino)methyl]phenol, also known as "DMPA," is a compound of considerable interest within various fields of chemistry and industry. Here are some fascinating insights about this compound:

  • Structure and Reactivity: DMPA features a unique arrangement of functional groups, which gives it promising reactivity profiles. The presence of a dimethylamino group contributes to its ability to act as a nucleophile, allowing it to participate in a range of chemical reactions.
  • Protonation Behavior: The dimethylamino group can be protonated under acidic conditions, enhancing the compound's utility in catalytic processes and influencing its solubility in various solvents. This characteristic highlights DMPA's versatility across acidic and basic environments.
  • Application in Synthesis: DMPA serves as an important intermediate in the synthesis of various organic compounds. Its ability to form hydrogen bonds can be exploited in the creation of polymers and other materials.
  • Role in Pharmaceuticals: Many derivatives of phenolic compounds, including DMPA, have been explored for their biological activity. The potential medicinal properties attributed to this compound make it a subject of investigation for drug development.
  • Environmental Chemistry: DMPA is also relevant in environmental studies, as phenolic compounds can act as indicators of pollution and can be involved in bioremediation processes.

In summary, the compound 2-[(dimethylamino)methyl]phenol brings a wealth of possibilities in both chemical synthesis and application. As research continues to unfold, the significance of compounds like DMPA in advancing science and technology will undoubtedly become more pronounced.

Synonyms
2-((Dimethylamino)methyl)phenol
120-65-0
2-(Dimethylaminomethyl)phenol
2-[(dimethylamino)methyl]phenol
o-(Dimethylaminomethyl)phenol
Phenol, 2-((dimethylamino)methyl)-
alpha-(Dimethylamino)-o-cresol
DTXSID3041293
NSC-12220
111113M8RT
DTXCID8021199
Phenol, 2-[(dimethylamino)methyl]-
RefChem:1060576
204-413-9
2-Dimethylaminomethylphenol
N,N-Dimethyl-2-hydroxybenzylamine
alpha-Dimethylamino-o-cresol
(2-Hydroxybenzyl)dimethylamine
DMP-10
alpha-(Dimethylamino)-cresol
.alpha.-(Dimethylamino)-o-cresol
2-Dimethylaminomethylphenol (contains phenol)
UNII-111113M8RT
NSC12220
EINECS 204-413-9
MFCD00045793
NSC 12220
o-dimethylaminomethylphenol
2-Dimethylaminomethyl phenol
Oprea1_028196
SCHEMBL116610
SCHEMBL7188042
SCHEMBL9424753
CHEMBL3182353
SCHEMBL16720626
SCHEMBL16720628
SCHEMBL29354255
o-Cresol, alpha-(dimethylamino)-
Phenol, ((dimethylamino)methyl)-
phenol, 2-(dimethylaminomethyl)-
2-(N,N-dimethylaminomethyl)phenol
EINECS 246-866-5
Tox21_301544
((DIMETHYLAMINO)METHYL)PHENOL
o-Cresol, .alpha.-(dimethylamino)-
STL060847
AKOS005216435
SB75742
NCGC00255421-01
O-HYDROXY-N,N-DIMETHYLBENZYLAMINE
CAS-120-65-0
DB-301975
2-[(Dimethylamino)methyl]phenol, AldrichCPR
CS-0442250
D0655
NS00021567
Q27251199