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Dimethylaminomethylphenol

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Identification
Molecular formula
C9H13NO
CAS number
2531-61-9
IUPAC name
2-[(dimethylamino)methyl]phenol;3-[(dimethylamino)methyl]phenol;4-[(dimethylamino)methyl]phenol
State
State

At room temperature, dimethylaminomethylphenol compounds typically exist as a liquid. They are known to be stable under normal conditions and exhibit properties characteristic of aromatic amines.

Melting point (Celsius)
5.00
Melting point (Kelvin)
278.15
Boiling point (Celsius)
257.43
Boiling point (Kelvin)
530.58
General information
Molecular weight
151.21g/mol
Molar mass
151.2120g/mol
Density
1.0450g/cm3
Appearence

Dimethylaminomethylphenol compounds appear as colorless or pale yellow liquids. They may have a characteristic amine odor. These compounds are known for their hygroscopic nature, meaning they readily absorb moisture from the air.

Comment on solubility

Solubility of 2-[(dimethylamino)methyl]phenol, 3-[(dimethylamino)methyl]phenol, and 4-[(dimethylamino)methyl]phenol

The solubility characteristics of 2-[(dimethylamino)methyl]phenol, 3-[(dimethylamino)methyl]phenol, and 4-[(dimethylamino)methyl]phenol are influenced by their structural configurations and functional groups. Here are some key points regarding their solubility:

  • Polar Nature: The presence of the dimethylamino group enhances the polarity of these compounds, making them more soluble in polar solvents.
  • Solvent Interaction: These phenolic compounds can dissolve well in water due to hydrogen bonding capabilities, but their solubility may vary depending on the specific position of the dimethylamino group.
  • Temperature Dependence: Like many organic molecules, their solubility can be affected by temperature. Generally, increased temperature tends to improve solubility.
  • Position of Substitution: The position of the dimethylamino group relative to the hydroxyl group can affect steric hindrance and solvation, impacting solubility in different solvents.

In summary, while all three compounds exhibit decent solubility in water and other polar solvents, their precise solubility levels can differ based on multiple factors. Understanding these nuances can be crucial for their applications in various chemical contexts.

Interesting facts

Interesting Facts about 2-[(dimethylamino)methyl]phenol, 3-[(dimethylamino)methyl]phenol, and 4-[(dimethylamino)methyl]phenol

The compounds 2-[(dimethylamino)methyl]phenol, 3-[(dimethylamino)methyl]phenol, and 4-[(dimethylamino)methyl]phenol are fascinating members of the phenolic family. These compounds, known collectively as dimethylaminomethylphenols, have garnered attention due to their unique structural features and versatile applications.

Structural Isomers

One of the intriguing aspects of these compounds is that they are structural isomers. Despite having the same molecular formula, the differing positions of the hydroxymethyl group relative to the amine nitrogen lead to variations in:

  • Biological Activity: Depending on their specific arrangement, these compounds can exhibit different levels of pharmacological activity.
  • Chemical Reactivity: The position of the functional groups can greatly influence how these compounds react under various conditions.
  • Material Properties: The isomer's properties can affect their usefulness in the development of specialty chemicals and materials.

Applications

These compounds have found diverse applications in various industries, including:

  • Pharmaceuticals: They are often utilized as intermediates in the synthesis of medicinal compounds due to their potential pharmacological effects.
  • Colorants: The dimethylamino group enhances their use in dyes and pigments, contributing to vivid colors in products.
  • Chemical Synthesis: Their reactivity makes them valuable substrates for further chemical transformations in organic synthesis.

Biological Insights

The biological implications of dimethylaminomethylphenols are noteworthy:

  • Research into their mechanism of action has revealed potential effects on neurotransmitter systems.
  • Study of these compounds aids in understanding complex biological pathways and may contribute to the development of new therapeutic agents.

To summarize, 2-[(dimethylamino)methyl]phenol, 3-[(dimethylamino)methyl]phenol, and 4-[(dimethylamino)methyl]phenol present a rich arena for both scientific exploration and industrial application. Their structural nuances not only influence their chemical behavior but also underline their significance in modern chemistry and biology.