Skip to main content

Procaine

ADVERTISEMENT
Identification
Molecular formula
C13H20N2O2
CAS number
59-46-1
IUPAC name
2-(dipropylamino)ethyl 4-aminobenzoate
State
State

At room temperature, Procaine is typically found as a solid in the form of a crystalline powder.

Melting point (Celsius)
61.00
Melting point (Kelvin)
334.15
Boiling point (Celsius)
378.30
Boiling point (Kelvin)
651.45
General information
Molecular weight
236.31g/mol
Molar mass
236.3110g/mol
Density
1.1762g/cm3
Appearence

Procaine appears as a white crystalline powder. It is soluble in water and has a slightly bitter taste. Being an anesthetic, this compound is used in various medical applications for numbing. Upon exposure to air and light, it may gradually become discolored.

Comment on solubility

Solubility of 2-(dipropylamino)ethyl 4-aminobenzoate

The solubility of 2-(dipropylamino)ethyl 4-aminobenzoate can be influenced by several factors, including its molecular structure and the nature of the solvent used. Key points to consider regarding its solubility include:

  • Polarity: The presence of amino functional groups within the molecule contributes to its polar nature, potentially enhancing solubility in polar solvents like water.
  • Hydrophobic Components: The dipropylamino group is relatively hydrophobic, suggesting that this compound may show significant solubility in organic solvents such as ethanol or acetone.
  • pH Dependency: Solubility can vary with pH changes, as the amino groups may become protonated in acidic conditions, affecting their interaction with solvents.
  • Temperature Effects: Increased temperature typically enhances solubility, allowing for better dissolution in the chosen solvent.

In summary, while 2-(dipropylamino)ethyl 4-aminobenzoate exhibits characteristics that suggest varied solubility behavior across different solvents, it is essential to consider each of these factors when predicting its solubility. As noted, polar and non-polar aspects can lead to unique solvation interactions that are crucial in practical applications.

Interesting facts

Interesting Facts about 2-(Dipropylamino)ethyl 4-aminobenzoate

2-(Dipropylamino)ethyl 4-aminobenzoate is a fascinating compound widely recognized in the field of medicinal chemistry. Here are some intriguing aspects to consider:

  • Pharmaceutical Applications: This compound is often studied for its potential pharmaceutical applications, particularly as a local anesthetic or in the formulation of other drugs.
  • Structure-Activity Relationship (SAR): The unique structure of this compound, featuring a dipropylamino group, has garnered attention for its ability to enhance biological activity. Scientists analyze how slight modifications in the chemical structure can lead to varying effects on biological systems.
  • Mechanism of Action: Research suggests that compounds like 2-(dipropylamino)ethyl 4-aminobenzoate may function by blocking sodium channels, which are crucial for the initiation and conduction of nerve impulses, leading to local anesthetic effects.
  • Research Context: In studies, scientists often compare this compound to other amino benzoate derivatives. Such comparisons help in understanding its efficacy and safety profile better, making it a valuable model in drug design and development work.

In summary, 2-(dipropylamino)ethyl 4-aminobenzoate exemplifies the intersection of chemical structure and therapeutic function, highlighting the complexities that make medicinal chemistry both challenging and rewarding. As one researcher aptly noted, "the magic of chemistry lies in how tiny changes can create profoundly different results."