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Procaine Hydrochloride

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Identification
Molecular formula
C13H21ClFN2O2
CAS number
51-05-8
IUPAC name
2-(dipropylamino)ethyl 4-fluorobenzoate;hydrochloride
State
State

Procaine hydrochloride is in a solid state at room temperature, typically available as a powder.

Melting point (Celsius)
154.00
Melting point (Kelvin)
427.15
Boiling point (Celsius)
215.00
Boiling point (Kelvin)
488.15
General information
Molecular weight
272.77g/mol
Molar mass
343.8610g/mol
Density
1.1200g/cm3
Appearence

Procaine hydrochloride is typically a white, crystalline powder that is odorless. When dissolved in water or alcohol, it forms a clear, colorless solution. It's often used in medical settings or laboratories.

Comment on solubility

Solubility of 2-(Dipropylamino)ethyl 4-fluorobenzoate; Hydrochloride

The compound 2-(dipropylamino)ethyl 4-fluorobenzoate; hydrochloride exhibits notable solubility characteristics that are of interest in various applications.

Solubility Profile

  • Solvent Compatibility: This compound is generally soluble in polar solvents, indicating a preference for environments that can stabilize ionic interactions.
  • Aqueous Solubility: As a hydrochloride salt, it tends to have increased solubility in water compared to its non-salt form. This property makes it useful in pharmaceutical formulations.
  • Factors Influencing Solubility:
    • Temperature: Increasing the temperature typically enhances solubility for many salts.
    • pH Levels: The solubility may also be affected by the pH of the solution, as changes in pH can alter the ionization state.
  • Solubility Limitations: While soluble in water, it may have limited solubility in non-polar organic solvents, which can restrict its applications in certain contexts.

In conclusion, the solubility of 2-(dipropylamino)ethyl 4-fluorobenzoate; hydrochloride is a critical aspect that influences its behavior in biological systems and its utility in medicinal chemistry. As Dr. Solubility once stated, "A compound's effectiveness often depends not just on its structure, but also on its solubility."

Interesting facts

Interesting Facts about 2-(Dipropylamino)ethyl 4-fluorobenzoate; Hydrochloride

The compound 2-(dipropylamino)ethyl 4-fluorobenzoate; hydrochloride is a fascinating member of the class of compounds known as benzoates. Here are some compelling aspects of this intriguing chemical:

  • Pharmaceutical Relevance: This compound is often explored in drug development due to its potential to act as a pharmacological agent. The presence of the 4-fluoro group adds interesting properties such as increased metabolic stability and the possibility of enhanced biological activity.
  • Amine Functionality: The dipropylamino side chain can significantly influence the compound's ability to cross biological membranes, making it important for its bioavailability.
  • Structure-Activity Relationship: Researchers study this compound to better understand how variations in its structure might affect its pharmacological properties, which has implications in designing more effective drugs.
  • Role in Synthesis: This compound can serve as a building block in organic synthesis, where its unique properties allow it to facilitate the creation of more complex molecules.
  • Safety and Handling: As with many chloride salts, understanding its handling and safety protocols is essential, particularly in laboratory environments.

In summary, 2-(dipropylamino)ethyl 4-fluorobenzoate; hydrochloride is a compound that bridges organic chemistry and pharmacology, inviting chemists to explore its myriad possibilities. Its functionality and structure embody the delicate dance between chemical properties and biological effects—an exciting frontier for chemists and pharmacologists alike.

Synonyms
Dipropylaminoethyl p-fluorobenzoate hydrochloride
326-39-6
BENZOIC ACID, p-FLUORO-, DIPROPYLAMINOETHYL ESTER, HYDROCHLORIDE
p-Fluorobenzoic acid dipropylaminoethyl ester hydrochloride
DTXSID80186290
DTXCID90108781