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Clomipramine

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Identification
Molecular formula
C19H23ClN2O
CAS number
303-49-1
IUPAC name
but-2-enedioic acid;2-[(4-chlorophenyl)-(2-pyridyl)methoxy]-N,N-dimethyl-ethanamine
State
State

Clomipramine is at room temperature a solid. It's typically stable under normal conditions and can be stored safely without risk of it turning into a liquid or gas. The solid state is crucial for accurate dosing in its therapeutic applications, especially as it is usually formulated into tablets or capsules.

Melting point (Celsius)
188.00
Melting point (Kelvin)
461.20
Boiling point (Celsius)
280.50
Boiling point (Kelvin)
553.70
General information
Molecular weight
314.86g/mol
Molar mass
314.8270g/mol
Density
1.2950g/cm3
Appearence

Clomipramine is typically encountered as a white to off-white crystalline powder. Its appearance is quite common to many pharmaceutical compounds, presented in a fine granular form. This allows for more effective dissolution and absorption when ingested.

Comment on solubility

Solubility of But-2-enedioic Acid; 2-[(4-Chlorophenyl)-(2-Pyridyl)methoxy]-N,N-dimethyl-ethanamine

Understanding the solubility of chemical compounds is crucial for their application in various fields, including pharmaceuticals and materials science. In the case of but-2-enedioic acid and its derivative 2-[(4-chlorophenyl)-(2-pyridyl)methoxy]-N,N-dimethyl-ethanamine, we see some interesting characteristics:

  • But-2-enedioic acid (also known as fumaric acid) is typically soluble in water due to its ability to form hydrogen bonds.
  • This solubility is enhanced by the presence of its carboxylic acid groups, which can readily interact with polar solvents.
  • The 2-[(4-chlorophenyl)-(2-pyridyl)methoxy]-N,N-dimethyl-ethanamine moiety, depending on its specific structure and functional groups, may exhibit varying solubility.

In general, the solubility of a compound can depend on several factors:

  1. Temperature: Higher temperatures can increase solubility for many organic compounds.
  2. Polarity: The compatibility between the polar/non-polar nature of solvents and solutes plays a significant role.
  3. Functional Groups: The presence of ionizable or polar functional groups can greatly enhance solubility in aqueous solutions.

As we analyze but-2-enedioic acid and its derivative, one must consider the context in which these compounds are intended to be used. In some cases, enhancing solubility through structural modifications may be beneficial. Therefore, understanding the exact nature of solubility can lead to improved applications and effectiveness in various chemical processes.

Interesting facts

Interesting Facts about but-2-enedioic acid; 2-[(4-chlorophenyl)-(2-pyridyl)methoxy]-N,N-dimethyl-ethanamine

But-2-enedioic acid, commonly known as maleic acid, is an important organic compound with significant applications in various fields. Here are some fascinating aspects:

Chemical Properties and Uses

  • Reactivity: Maleic acid is a diene, which means it readily undergoes addition reactions. This makes it a valuable intermediate in the synthesis of a range of compounds.
  • Applications: It is widely utilized in the production of resins, coatings, and plastics. Additionally, it plays a vital role in the manufacturing of food additives and pharmaceuticals.
  • Versatility: This compound can be easily transformed into various derivatives, leading to a host of potential applications in organic chemistry.

Historical Significance

Initially isolated in the 19th century, maleic acid has piqued the interest of chemists for its distinctive structure and reactivity. As one of the simplest unsaturated dicarboxylic acids, it serves as a fundamental building block in organic synthesis.

Health and Safety

While but-2-enedioic acid has significant industrial applications, it is essential to handle it with care due to its irritant properties. Proper safety measures must be observed to ensure safe handling in laboratory and industrial settings.

Innovative Applications

  • Maleic acid has been explored for use in biodegradable plastics, contributing to the reduction of environmental impact.
  • Research continues into how it can be used in pharmaceutical formulations, enhancing drug delivery systems.

Overall, but-2-enedioic acid, along with its derivatives such as 2-[(4-chlorophenyl)-(2-pyridyl)methoxy]-N,N-dimethyl-ethanamine, reflects the complexity and ingenuity of organic chemistry. Its applications across various industries highlight the essential role of chemical compounds in our daily lives.

Synonyms
2-((4-Chlorophenyl)(pyridin-2-yl)methoxy)-n,n-dimethylethan-1-amine but-2-enedioate
Ethanamine, 2-[(4-chlorophenyl)-2-pyridinylmethoxy]-N,N-dimethyl-,(2Z)-2-butenedioate (1:1)
PD055994
NS00084041
But-2-enedioic acid {2-[(4-chlorophenyl)(pyridin-2-yl)methoxy]ethyl}dimethylamine
but-2-enedioic acid;2-[(4-chlorophenyl)-pyridin-2-ylmethoxy]-N,N-dimethylethanamine