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Promethazine fumarate

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Identification
Molecular formula
C20H20N2O2 · C4H4O4
CAS number
60-87-7
IUPAC name
but-2-enedioic acid;3-(2-methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine
State
State
Promethazine fumarate is typically in a solid state at room temperature, appearing as a powder.
Melting point (Celsius)
235.00
Melting point (Kelvin)
508.15
Boiling point (Celsius)
274.00
Boiling point (Kelvin)
547.15
General information
Molecular weight
380.48g/mol
Molar mass
380.4810g/mol
Density
1.1960g/cm3
Appearence

Promethazine fumarate is typically a white to faint yellow crystalline powder. It is odorless or may have a faint characteristic odor.

Comment on solubility

Solubility of but-2-enedioic acid; 3-(2-methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine

Understanding the solubility of the compound but-2-enedioic acid; 3-(2-methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine is essential for its applications in both laboratory and industrial settings. Solubility can be influenced by various factors, including its structure, functional groups, and the presence of specific solvation interactions. This compound is characterized by:

  • Polarity: The presence of polar functional groups in the molecule can enhance solubility in polar solvents, such as water.
  • Hydrogen Bonding: If the compound can participate in hydrogen bonding, this can significantly increase its solubility in polar solvents.
  • Van der Waals Forces: The presence of aromatic rings can affect how the compound interacts with nonpolar solvents.

As a result, the expected solubility is likely to be:

  • High in: Water and other polar solvents due to the presence of polar bonds.
  • Low in: Nonpolar solvents, which may struggle to solvate the compound effectively.

Furthermore, it is crucial to note that the solubility might vary with temperature and pH, and precise measurements should be made for definitive conclusions. As a general rule, "like dissolves like," meaning that a polar compound will have a much better chance of dissolving in a polar solvent than in a nonpolar one.

Interesting facts

Exploring But-2-enedioic Acid and Its Derived Compound

But-2-enedioic acid, commonly known as maleic acid, is a fascinating organic compound with a range of applications in various industries. Here are some intriguing facts about this compound and its derivatives:

  • Chemical Versatility: But-2-enedioic acid is a key player in the synthesis of a variety of compounds, acting as a precursor in the production of pharmaceuticals, agrochemicals, and surfactants.
  • Reactivity: It readily undergoes reactions such as hydrogenation, polymerization, and esterification, showcasing its ability to transform into diverse chemical entities.
  • Health Applications: Maleic acid's derivatives play an important role in medicine, particularly in drug formulation, where they can enhance the bioavailability of certain therapeutic agents.
  • Ecological Significance: The compound is also studied in relation to its effects on the environment, particularly in the degradation processes of organic materials.

3-(2-Methoxyphenothiazin-10-yl)-N,N-dimethyl-propan-1-amine

This compound is an interesting derivative of but-2-enedioic acid and incorporates a phenothiazine structure, which is significant in medicinal chemistry.

  • Pharmaceutical Interests: The phenothiazine moiety is associated with antipsychotic effects, making this compound a subject of research in developing new neuroleptic drugs.
  • Synthetic Pathways: The incorporation of N,N-dimethyl and propan-1-amine groups provides unique pathways for synthetic chemists to explore more complex modifications and biological activities.
  • Potential Activities: Compounds like this are often investigated for their antioxidant properties, which may contribute to therapeutic benefits in various medical conditions.

As a student or scientist delving into the world of organic chemistry, both but-2-enedioic acid and its derivatives present a rich landscape of chemical behaviors and potential applications, allowing us to appreciate the intricate relationships between structure and function in organic molecules.

Synonyms
10-[3-(DIMETHYLAMMONIO)PROPYL]-2-METHOXY-10H-PHENOTHIAZINIUM MALEATE
3403-42-7