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Nicotine maleate

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Identification
Molecular formula
C10H15N2O.C4H4O4
CAS number
65-31-6
IUPAC name
but-2-enedioic acid;(5R)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one
State
State

At room temperature, nicotine maleate is a solid state compound often used in pharmacological studies and applications.

Melting point (Celsius)
159.00
Melting point (Kelvin)
432.15
Boiling point (Celsius)
618.15
Boiling point (Kelvin)
891.30
General information
Molecular weight
222.26g/mol
Molar mass
222.2550g/mol
Density
1.0555g/cm3
Appearence

Nicotine maleate typically appears as a crystalline solid with a slight tan color. It is often used in the form of salt crystals.

Comment on solubility

Solubility of But-2-enedioic Acid and (5R)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one

When examining the solubility characteristics of the compounds but-2-enedioic acid (C4H4O4) and (5R)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one (C10H12N2O), it’s important to consider several factors:

But-2-enedioic Acid

But-2-enedioic acid, commonly known as maleic acid, is a dicarboxylic acid that is generally soluble in water. Its solubility can be attributed to the following:

  • Polarity: The presence of two carboxylic acid groups enhances its ability to interact with water molecules.
  • Hydrogen Bonding: These functional groups can form hydrogen bonds, increasing solubility in polar solvents.
  • Temperature Dependency: Solubility increases with temperature, which is a common trait for many organic acids.

However, it is less soluble in non-polar solvents, highlighting its preference for polar environments.

(5R)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one

The solubility of (5R)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one in water is not as straightforward to define. Factors influencing its solubility include:

  • Pyridine Ring: The presence of the pyridine moiety can enhance solubility in organic solvents but can also create a degree of polarity.
  • Molecular Weight: Higher molecular weights typically correlate with lower solubility in water.
  • Functional Groups: The specific arrangement of substituents may influence intermolecular interactions, affecting solubility characteristics.

In general, it may exhibit moderate solubility in organic solvents and limited solubility in water, depending on the molecular interactions.

In conclusion, while but-2-enedioic acid demonstrates consistent water solubility due to its polar nature, (5R)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one may require a more detailed analysis to understand its solubility behavior in various solvents.

Interesting facts

Interesting Facts about But-2-enedioic Acid and (5R)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one

But-2-enedioic acid, commonly known as fumaric acid, is an important organic compound. Here are a few remarkable aspects:

  • Biological Significance: Fumaric acid plays a crucial role in the Krebs cycle, which is vital for cellular respiration and energy production in living cells.
  • Therapeutic Uses: It is used as a treatment for conditions like psoriasis and multiple sclerosis. Its therapeutic action is believed to be linked to its ability to modulate immune responses.
  • Natural Sources: This compound can be found in various plants, especially in the form of its salts (fumarates), which are often more biologically active.

On the other hand, (5R)-1-methyl-5-(3-pyridyl)pyrrolidin-2-one is a compound with distinct properties:

  • Structural Complexity: The structure features a pyridine ring fused with a pyrrolidine, which enhances its biological activity.
  • Potential Applications: This compound has been investigated for its potential in treating neurological disorders and various psychotropic effects.
  • Chirality: As a chiral molecule, it exists as two enantiomers, and only one may exhibit the desired biological activity, which is essential in pharmaceutical applications.

In summary, both of these compounds hold fascinating properties that contribute to their significance in the fields of chemistry and medicine. Their diverse applications and biological roles make them subjects of ongoing research and interest for scientists and students alike!