Skip to main content

Chlordiazepoxide

ADVERTISEMENT
Identification
Molecular formula
C16H14ClN3O
CAS number
58-25-3
IUPAC name
but-2-enedioic acid;7-chloro-5-phenyl-1-(2-piperazin-1-ylethyl)-3H-1,4-benzodiazepin-2-one
State
State

At room temperature, chlordiazepoxide is a solid. It is used in the form of its hydrochloride salt as a medication.

Melting point (Celsius)
231.50
Melting point (Kelvin)
504.65
Boiling point (Celsius)
500.15
Boiling point (Kelvin)
773.30
General information
Molecular weight
299.76g/mol
Molar mass
299.7630g/mol
Density
1.4001g/cm3
Appearence

Chlordiazepoxide typically appears as a white or almost white crystalline powder. It is practically odorless and has a bitter taste.

Comment on solubility

Solubility of But-2-enedioic Acid; 7-Chloro-5-phenyl-1-(2-piperazin-1-ylethyl)-3H-1,4-benzodiazepin-2-one

Understanding the solubility of this compound is crucial for its applications in various fields, particularly in pharmaceuticals. The solubility of but-2-enedioic acid (also known as maleic acid) is influenced by its carboxylic acid functional groups, allowing it to dissolve readily in polar solvents. Here are some key points regarding its solubility:

  • Soluble in water due to the ability to form hydrogen bonds.
  • Also soluble in organic solvents such as alcohols and ethers.
  • Low solubility in non-polar solvents, such as hydrocarbons.

The second component, 7-chloro-5-phenyl-1-(2-piperazin-1-ylethyl)-3H-1,4-benzodiazepin-2-one, encounters a more complex solubility landscape primarily due to its bulky structure and the presence of multiple functional groups. Consider the following aspects:

  • Moderate solubility in polar solvents, particularly in methanol and DMSO.
  • Can be less soluble in water due to its large aromatic and piperazine rings.
  • May exhibit increased solubility in mixed solvents or with the addition of solubilizing agents.

In summary, the solubility of this compound is a balancing act between its polar and non-polar characteristics, greatly influencing its efficacy and bioavailability in medicinal applications. As emphasized, this dual nature makes the study of its solubility essential for understanding behavior in biological systems.

Interesting facts

Interesting Facts about But-2-enedioic Acid and Its Derivatives

But-2-enedioic acid, commonly known as fumaric acid, is an intriguing compound that plays a significant role in various biochemical and industrial processes. Below are some interesting facts about this compound and its derivatives:

  • Key Metabolite: But-2-enedioic acid is an important intermediate in the Krebs cycle, a crucial metabolic pathway for energy production in cellular respiration.
  • Therapeutic Potential: Research has demonstrated its potential therapeutic effects, especially in the treatment of conditions such as multiple sclerosis and psoriasis.
  • Industrial Applications: It is used in the synthesis of various polymers, including resins and plastics. Fumaric acid can also act as a food additive to impart a sour flavor.
  • Environmental Significance: This compound can be produced via eco-friendly biological processes, highlighting its potential in sustainable chemistry.

The compound also has an intriguing derivative: 7-chloro-5-phenyl-1-(2-piperazin-1-ylethyl)-3H-1,4-benzodiazepin-2-one, which belongs to the benzodiazepine family. Here are some noteworthy aspects:

  • Pharmacological Activity: This derivative exhibits pronounced effects on the central nervous system, often being studied for its anxiolytic and sedative properties.
  • Structure-Activity Relationship: Its unique molecular structure allows for varied interactions with neurotransmitter receptors, making it a crucial subject for medicinal chemistry research.
  • Drug Development: Compounds of this type are significant in the development of new medications targeted towards neurological disorders.

In conclusion, both but-2-enedioic acid and its derivatives showcase valuable properties that bridge the gap between fundamental research and practical applications in medicine and industry. As scientists continue to explore these compounds, their contributions to advancement in health and sustainability remain impressive.