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Diazepam

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Identification
Molecular formula
C16H13ClN2O2
CAS number
439-14-5
IUPAC name
but-2-enedioic acid;7-chloro-5-phenyl-1-(2-pyrrolidin-1-ylethyl)-3H-1,4-benzodiazepin-2-one
State
State

Solid at room temperature.

Melting point (Celsius)
131.00
Melting point (Kelvin)
404.15
Boiling point (Celsius)
366.90
Boiling point (Kelvin)
640.05
General information
Molecular weight
284.74g/mol
Molar mass
284.7400g/mol
Density
1.4200g/cm3
Appearence

Diazepam is typically found as a crystalline powder and is white to off-white in appearance. It is odorless, or nearly so.

Comment on solubility

Solubility of but-2-enedioic acid; 7-chloro-5-phenyl-1-(2-pyrrolidin-1-ylethyl)-3H-1,4-benzodiazepin-2-one

The solubility of the compound but-2-enedioic acid; 7-chloro-5-phenyl-1-(2-pyrrolidin-1-ylethyl)-3H-1,4-benzodiazepin-2-one can be considered through several key aspects:

  • Polarity: This compound features polar functional groups including carboxylic acid and amine groups, which generally enhance solubility in polar solvents like water.
  • Hydrophobic regions: The presence of phenyl and pyrrolidine moieties contributes to hydrophobic interactions, potentially reducing solubility in aqueous solutions.
  • pH dependency: The solubility of but-2-enedioic acid, a dicarboxylic acid, may increase in alkaline conditions due to deprotonation, leading to more charged species that are more soluble in water.

In summary, the solubility behavior of this compound may exhibit a complex interplay between its polar and non-polar characteristics. According to solubility rules, compounds having both polar and non-polar sections are often categorized as having limited solubility in water but may dissolve well in organic solvents. Thus, it is essential to assess the solubility in various solvents to fully comprehend its chemical behavior.

Interesting facts

Interesting Facts about but-2-enedioic acid; 7-chloro-5-phenyl-1-(2-pyrrolidin-1-ylethyl)-3H-1,4-benzodiazepin-2-one

In the realm of organic chemistry, the compound but-2-enedioic acid; 7-chloro-5-phenyl-1-(2-pyrrolidin-1-ylethyl)-3H-1,4-benzodiazepin-2-one presents a fascinating blend of functionalities and medicinal properties. Here are some captivating insights:

  • Dual Nature: This compound features both a dicarboxylic acid and a complex benzodiazepine structure, illustrating a unique intersection of organic chemistry and pharmacology.
  • Bioactive Potential: The benzodiazepine backbone is known for its psychoactive properties, often utilized in anti-anxiety medications. Thus, this compound could have intriguing implications for the development of new therapeutic agents.
  • Chlorine Substitution: The presence of a chlorine atom in the structure can significantly influence the compound's reactivity and pharmacodynamics, often enhancing its interaction with biological targets.
  • Incorporation of Pyrrolidine: The addition of a pyrrolidine moiety can affect the molecular conformation, which may improve lipophilicity and overall biological activity.
  • Synthesis Challenges: The combination of these reactive groups necessitates tailored synthetic routes—highlighting the importance of understanding reaction mechanisms and stability when designing complex molecules.

As researchers and students delve into the intricacies of this compound, they may reflect on its multifaceted characteristics that echo the beauty of chemical creativity: "In the world of molecules, simplicity is often a facade; complexity reveals the true artistry of chemistry."

Overall, but-2-enedioic acid; 7-chloro-5-phenyl-1-(2-pyrrolidin-1-ylethyl)-3H-1,4-benzodiazepin-2-one stands as a remarkable example of how diverse chemical structures can converge to propel advancements in pharmaceutical science and medicinal chemistry.