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Fumaric Acid; Furmethide

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Identification
Molecular formula
C4H4O4; C14H19N3O
CAS number
110-17-8; 494-37-3
IUPAC name
but-2-enedioic acid;N'-(2-furylmethyl)-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine
State
State

At room temperature, fumaric acid is in a solid state. It is stable under normal conditions but can react with bases and oxidizing agents.

Melting point (Celsius)
287.00
Melting point (Kelvin)
560.00
Boiling point (Celsius)
300.00
Boiling point (Kelvin)
573.00
General information
Molecular weight
116.07g/mol
Molar mass
116.0720g/mol
Density
1.6300g/cm3
Appearence

Fumaric acid appears as a white crystalline powder. It is odorless and has a slightly acidic taste. The compound is notable for its role in the food industry as an acidity regulator and is often found in beverages and baking powders.

Comment on solubility

Solubility of But-2-enedioic Acid

But-2-enedioic acid, also known as maleic acid, exhibits interesting solubility characteristics. This compound is quite soluble in water, making it useful in various applications, especially in organic synthesis. Its solubility can be attributed to the formation of hydrogen bonds with water molecules due to its carboxylic acid groups.

Factors Affecting Solubility:

  • pH of Water: The solubility can increase at higher pH levels where maleic acid can deprotonate.
  • Temperature: Generally, increasing temperature enhances the solubility of organic acids.
  • Presence of Salts: The addition of salts may also change solubility through a phenomenon known as the "salting out" effect.

Maleic acid’s compatibility with water makes it suitable for use as a polymer precursor and in various industrial applications.

Solubility of N'-(2-furylmethyl)-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine

N'-(2-furylmethyl)-N,N-dimethyl-N'-(2-pyridyl)ethane-1,2-diamine presents a more complex solubility profile due to its intricate structure involving both furan and pyridine rings. Here are some key points about its solubility:

Solubility Highlights:

  • The compound is generally less soluble in water compared to simple carboxylic acids.
  • It is more likely to dissolve in organic solvents such as ethanol, ether, and acetone.
  • Hydrogen bonding and dipole interactions with solvents play a crucial role in its solubility.

Understanding the solubility of such compounds is crucial for their application in medicinal chemistry and materials science, where solvent interactions can greatly influence reaction conditions and outcomes.

Interesting facts

Exploring But-2-enedioic Acid

But-2-enedioic acid, commonly known as maleic acid, is a fascinating compound that serves multiple roles in both scientific research and practical applications. Here are some key facts:

  • Chemical Versatility: It is a crucial intermediate in the synthesis of many organic compounds, including resins, flavorings, and colorants.
  • Sources: Maleic acid derives naturally from plant sources, which underscores its eco-friendly properties. However, it is typically produced synthetically.
  • Reactivity: The compound is known for its unique reactivity. It easily undergoes cis-trans isomerization due to its double bond, allowing chemists to create various derivatives.
  • Polymer Formation: A notable characteristic is its ability to polymerize into poly(maleic anhydride), which has applications in pharmaceuticals and plastics.

Introducing N'-(2-Furylmethyl)-N,N-Dimethyl-N'-(2-Pyridyl)ethane-1,2-Diamine

This compound presents a fascinating intersection between organic chemistry and medicinal applications, particularly due to its complex structure and substituent groups. Here are some of its intriguing aspects:

  • Unique Structure: Featuring both furyl and pyridyl groups, this compound exhibits interesting properties that arise from ring systems, potentially influencing its reactivity and biological activity.
  • Potential Biological Applications: Research suggests that compounds with similar structures may exhibit antimicrobial or antitumor activities, opening avenues for future medicinal chemistry studies.
  • Ligand Features: Its design as a diamine makes it capable of coordinating with metal ions, which is useful in various chemical reactions and catalysis.

As a student of chemistry, understanding the significance of these compounds enhances knowledge about how molecular configurations dictate chemical behavior and potential applications.