Skip to main content

2-Ethoxyacetic acid

ADVERTISEMENT
Identification
Molecular formula
C4H8O3
CAS number
110-80-5
IUPAC name
2-ethoxyacetic acid
State
State

At room temperature, 2-Ethoxyacetic acid typically exists as a liquid. Its hygroscopic nature means it absorbs moisture from the air, which can affect its state and appearance over time if not stored properly.

Melting point (Celsius)
-32.00
Melting point (Kelvin)
241.15
Boiling point (Celsius)
196.00
Boiling point (Kelvin)
469.15
General information
Molecular weight
104.10g/mol
Molar mass
104.1150g/mol
Density
1.1027g/cm3
Appearence

2-Ethoxyacetic acid is a colorless to pale yellow liquid. It is hygroscopic and has a mild, characteristic odor. The compound is often supplied in a stabilized form because it can discolor upon exposure to air and light.

Comment on solubility

Solubility of 2-ethoxyacetic acid

2-ethoxyacetic acid, with the chemical formula C4H8O3, exhibits interesting solubility characteristics due to its molecular structure. Here are some key points regarding its solubility:

  • Solvent Compatibility: 2-ethoxyacetic acid is known to be soluble in water because of its polar –OH (hydroxyl) group, which forms hydrogen bonds with water molecules.
  • Organic Solubility: This compound is also soluble in a variety of organic solvents such as ethers, alcohols, and ketones.
  • Temperature Effects: Its solubility can be affected by temperature; typically, higher temperatures enhance the solubility in both aqueous and organic environments.
  • pH Influence: The solubility improves in alkaline conditions as the acid can partially dissociate, increasing its ionic character.

In summary, the solubility of 2-ethoxyacetic acid is notable for its versatility across various solvents—a feature that is advantageous in applications within chemical synthesis and formulation. As a general rule, the presence of polar functional groups in a molecule generally enhances its solubility in polar solvents like water, making 2-ethoxyacetic acid a prime example of this phenomenon.

Interesting facts

Interesting Facts about 2-Ethoxyacetic Acid

2-Ethoxyacetic acid is an intriguing compound with a variety of applications and properties that make it noteworthy in the field of chemistry. Here are some fascinating aspects of this compound:

  • Versatile Solvent: 2-Ethoxyacetic acid is known for its effectiveness as a solvent in numerous organic reactions, making it a valuable tool in both laboratory and industrial settings.
  • Intermediate in Synthesis: This compound acts as an important intermediate in the synthesis of various chemical products, contributing to the creation of pharmaceuticals and agrochemicals.
  • Biological Significance: As a carboxylic acid, 2-ethoxyacetic acid can engage in hydrogen bonding, which can impact its interactions with biological systems, potentially influencing metabolism and bioavailability.
  • Laboratory Usage: In research, this compound has been utilized in studies investigating esterification reactions and the development of new polymers, highlighting its role in advancing the field of synthetic chemistry.
  • Safety Considerations: While 2-ethoxyacetic acid has practical uses, it is important for chemists to handle it with care, as it can be harmful upon exposure. Proper safety protocols should always be followed when working with this compound.

In conclusion, 2-ethoxyacetic acid may seem simple at first glance, but it exhibits a rich set of properties and applications that highlight its importance in both academic and industrial chemistry. As described by experts, "the ability of a compound to bridge functional diversity and practical application defines its true value in the scientific community."

Synonyms
ETHOXYACETIC ACID
2-Ethoxyacetic acid
Acetic acid, ethoxy-
Ethoxy acetic acid
O-Ethylglycolic acid
Acetic acid, 2-ethoxy-
CCRIS 7194
NSC 6750
EINECS 210-978-2
UNII-467VW095BX
BRN 1743037
DTXSID7031294
AI3-24145
467VW095BX
NSC-6750
DTXCID5011294
YZGQDNOIGFBYKF-UHFFFAOYSA-
2Ethoxyacetic acid
Acetic acid, ethoxy
Acetic acid, 2ethoxy
GLYCOLLIC ACID ETHYL ESTER
210-978-2
4-03-00-00574 (beilstein handbook reference)
inchi=1/c4h8o3/c1-2-7-3-4(5)6/h2-3h2,1h3,(h,5,6)
un3265
yzgqdnoigfbykf-uhfffaoysa-n
627-03-2
ethoxy-acetic acid
2-ethoxy-acetic acid
CAS-627-03-2
MFCD00004310
2-Ethoxyaceticacid
31621-87-1
Ethoxy-acetic acid anion
Ethoxyacetic acid, 98%
Glycolic acid ethyl ether
ETHOXYACETIC ACID (EGMEE (110-80-5))
SCHEMBL48574
RESOMER® X 206 S
CHEMBL1159929
NSC6750
CHEBI:173365
STR05191
Tox21_202431
Tox21_303384
STL166132
AKOS000120246
FP34560
HY-W027555
NCGC00090711-01
NCGC00090711-02
NCGC00257362-01
NCGC00259980-01
CS-0071579
E0377
Ethoxyacetic acid, purum, >=98.0% (GC)
NS00035134
EN300-21303
D73862
Q26841235
F2191-0091
Z104495232