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Etilefrine hydrobromide

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Identification
Molecular formula
C11H18NO2Br
CAS number
108-09-8
IUPAC name
2-ethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-5-ol;bromide
State
State

At room temperature, Etilefrine hydrobromide is in a solid state, typically appearing as a crystalline powder.

Melting point (Celsius)
191.00
Melting point (Kelvin)
464.15
Boiling point (Celsius)
364.15
Boiling point (Kelvin)
637.30
General information
Molecular weight
272.16g/mol
Molar mass
272.1620g/mol
Density
1.5000g/cm3
Appearence

Etilefrine hydrobromide appears as a white to off-white crystalline powder. The compound may also appear slightly hygroscopic, absorbing moisture from the air.

Comment on solubility

Solubility of 2-ethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-5-ol; bromide

The solubility of 2-ethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-5-ol; bromide can be influenced by various factors due to its unique chemical structure.

This compound is considered a quaternary ammonium salt, which generally exhibits good solubility in polar solvents. Specifically, its solubility characteristics include:

  • Solvent Type: It is typically soluble in water and other polar solvents due to the ionic nature of the bromide ion and the highly polarizable tetrahydroisoquinoline structure.
  • Temperature Dependency: As with many compounds, solubility may increase with rising temperature, enhancing the ability of the solvent to dissolve the solute.
  • pH Influence: The ionic strength and pH of the solution can also have a significant impact on solubility, potentially altering the protonation state of the compound.

Overall, it can be said that 2-ethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-5-ol; bromide is expected to exhibit considerable solubility in aqueous solutions, making it versatile for various applications. It’s crucial to consider these factors when working with this compound to maximize its effective solubility.

Interesting facts

Exploring 2-Ethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-5-ol Bromide

2-Ethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-5-ol bromide is a fascinating compound with intriguing properties and potential applications. As part of the isoquinoline family, this compound is characterized by its unique bicyclic structure, which inherently grants it interesting biological activity. Here are some noteworthy points to consider:

  • Biological Relevance: Isoquinolines have been studied for their potential roles in medicinal chemistry, particularly in the fields of neurology and psychiatry. Some derivatives exhibit promising effects as neuroprotective agents.
  • Structural Features: The tetrahydroisoquinoline backbone provides a nitrogen atom that can participate in various chemical reactions. This opens avenues for modifications and the development of analogs with enhanced properties.
  • Quaternization Effects: The presence of the quaternary ammonium group (the -ium part of the name) often influences solubility and the ability of the compound to cross biological membranes, making it of interest in drug development.
  • Research Potential: Due to its structural complexity, this compound continues to be a topic of research, looking into its interactions at the molecular level and its potential therapeutic benefits.

As a chemistry student or researcher, one should appreciate the interplay of structure and function in compounds like 2-ethyl-1,2,3,4-tetrahydroisoquinolin-2-ium-5-ol bromide. It serves as a prime example of how organic compounds can influence health and disease through their unique structures and biological activity. As the late chemist and Nobel laureate Linus Pauling said, "The best way to have a good idea is to have a lot of ideas." Exploring the myriad possibilities of this compound could very well lead to the next breakthrough in medicinal chemistry!

Synonyms
4512-82-7
2-Ethyl-5-hydroxy-1,2,3,4-tetrahydroisoquinoline, hydrobromide
5-ISOQUINOLINOL, 1,2,3,4-TETRAHYDRO-2-ETHYL-, HYDROBROMIDE
2-ethyl-5-hydroxy-1,2,3,4-tetrahydroisoquinolinium bromide