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Quinuclidine

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Identification
Molecular formula
C7H13N
CAS number
100-76-5
IUPAC name
2-ethyl-2-azabicyclo[2.2.1]heptane
State
State

Quinuclidine can be found as either a solid or a liquid at room temperature. It is hygroscopic, meaning it tends to absorb moisture from the air.

Melting point (Celsius)
158.00
Melting point (Kelvin)
431.15
Boiling point (Celsius)
149.00
Boiling point (Kelvin)
422.15
General information
Molecular weight
111.19g/mol
Molar mass
111.1870g/mol
Density
1.0112g/cm3
Appearence

Quinuclidine appears as a colorless to yellowish liquid or solid, depending on the ambient temperature. It has a characteristic, amine-like odor. When in its solid form, it usually appears crystalline.

Comment on solubility

Solubility of 2-ethyl-2-azabicyclo[2.2.1]heptane

The solubility of 2-ethyl-2-azabicyclo[2.2.1]heptane in various solvents is influenced by its unique molecular structure. Understanding its solubility characteristics can be crucial for its applications in pharmaceuticals and organic synthesis.

  • Polar Solvents: Generally, this compound exhibits low solubility in highly polar solvents such as water due to the limited ability of the molecule to interact favorably with water molecules.
  • Non-Polar Solvents: Conversely, 2-ethyl-2-azabicyclo[2.2.1]heptane tends to be more soluble in non-polar organic solvents, such as hexane or toluene, which allow for better interaction with its hydrocarbon structure.
  • Hydrogen Bonding: The presence of nitrogen in the bicyclic structure enables some level of hydrogen bonding; however, this characteristic alone does not significantly enhance its solubility in polar media.

In summary, the solubility of 2-ethyl-2-azabicyclo[2.2.1]heptane demonstrates a clear preference for non-polar environments, highlighting a fundamental principle in solubility where "like dissolves like." Understanding these affinities is vital for employing this compound effectively in various chemical contexts.

Interesting facts

Interesting Facts about 2-ethyl-2-azabicyclo[2.2.1]heptane

2-ethyl-2-azabicyclo[2.2.1]heptane, often referred to in the scientific community for its unique structural features, holds a significant place in the realm of organic chemistry. This compound is a bicyclic amine that can be classified under azabicycles, which are known for incorporating nitrogen into their ring structures. Here are some noteworthy aspects:

  • Structural Uniqueness: The presence of the bicyclic framework and an ethyl group attached to nitrogen provides interesting steric and electronic properties that can influence reactivity.
  • Applications in Synthesis: Compounds like this are often used as intermediates in organic synthesis, making them valuable in the production of pharmaceuticals and agrochemicals.
  • Biological Relevance: The nitrogen-containing bicyclic compounds are often explored in drug design due to their potential biological activity, particularly in treating neurological disorders.
  • Chirality Considerations: Depending on the specific reaction conditions and substituents, the chirality of this compound can be manipulated, which is crucial for the development of enantiomerically pure drugs.
  • Research Potential: Scientists are continually investigating new applications and reactions involving azabicyclic compounds, often leading to unexpected results that expand the field of organic chemistry.

To encapsulate the essence of this fascinating compound, one can say: "The journey of a simple nitrogen atom within a complex hydrocarbon structure opens doors to limitless opportunities in chemical innovation." The exploration of 2-ethyl-2-azabicyclo[2.2.1]heptane not only enriches our understanding of chemical bonding but also introduces new possibilities in various fields of study.

Synonyms
2-Ethyl-2-azabicyclo(2.2.1)heptane
NSC 94107
2-Ethyl-2-azabicyclo[2.2.1]heptane
BRN 1340705
2-AZABICYCLO(2.2.1)HEPTANE, 2-ETHYL-
2-Azabicyclo[2.2.1]heptane, 2-ethyl-
DTXSID80963301
5-20-04-00309 (Beilstein Handbook Reference)
DTXCID801391062
4492-38-0
NSC94107
SCHEMBL60067
NSC-94107
DS-000951