Skip to main content

Ethylhydroxamic acid

ADVERTISEMENT
Identification
Molecular formula
C12H18N2O2
CAS number
>0578764-47-2<
IUPAC name
2-ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide
State
State

At room temperature, 2-ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide is in a solid state. It is relatively stable when stored under normal conditions, though it should be protected from excessive moisture and light to prevent degradation. Handle typical of organic solids, with precautions for chemical sensitivity.

Melting point (Celsius)
173.00
Melting point (Kelvin)
446.15
Boiling point (Celsius)
323.40
Boiling point (Kelvin)
596.50
General information
Molecular weight
225.30g/mol
Molar mass
225.3050g/mol
Density
1.0302g/cm3
Appearence

2-Ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide typically appears as a crystalline solid. The compound's color may vary depending on the level of purity, often seen as a white to off-white color. The presence of the aromatic ring gives it a distinct structure that may be visible in well-formed crystals under magnification.

Comment on solubility

Solubility of 2-ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide

The solubility of 2-ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide can be influenced by various factors, including its molecular structure and functional groups. Generally, hydrazide compounds exhibit a range of polar and non-polar characteristics, which can impact their behavior in different solvents.

Key considerations for solubility include:

  • Polarity: The presence of the hydroxyl group (-OH) contributes to the molecule's polarity, potentially enhancing its solubility in polar solvents, such as water.
  • Hydrophobic Interactions: The ethyl and aromatic groups might create hydrophobic characteristics that could limit solubility in highly polar solvents.
  • Temperature Dependence: Solubility may be temperature-sensitive; generally, increasing temperature can increase solubility for many organic compounds.
  • pH Conditions: The solubility in water may also be affected by the pH of the solution, as ionic interactions could play a role when the compound is protonated or deprotonated.

In summary, the solubility of 2-ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide is multifaceted and can vary significantly based on the solvent environment, temperature conditions, and the chemical properties imparted by its functional groups. Understanding these factors is crucial for applications in synthesis and analysis.

Interesting facts

Exploring 2-Ethyl-2-Hydroxy-N'-(m-Tolyl)Butanehydrazide

2-Ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide is a fascinating compound that is attracting attention in the fields of organic synthesis and medicinal chemistry. Here are some intriguing facts about this unique chemical:

  • Functional Group Diversity: This compound contains multiple functional groups, including a hydrazide moiety and a hydroxyl group. These variations offer a plethora of opportunities for chemical reactivity and potential applications.
  • Hydrazide Chemistry: Hydrazides are known for their versatility. They often participate in various nucleophilic reactions, and their derivatives can exhibit significant biological activity, making them valuable in drug design.
  • Potential Applications: With the structural features of 2-ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide, researchers are investigating its potential use as an anti-inflammatory agent or as a scaffold for developing new pharmaceuticals.
  • Synthesis Pathway: The synthesis of this compound can involve multi-step organic reactions. The incorporation of the m-tolyl group suggests potential methods for tuning its properties by altering substituents on the aromatic ring.
  • Research Implications: As a part of ongoing research, compounds like this one can lead to a deeper understanding of structure-activity relationships in drug molecules, guiding the development of more effective therapies.

In conclusion, 2-ethyl-2-hydroxy-N'-(m-tolyl)butanehydrazide stands out not only for its structural complexity but also for its significant potential in medicinal chemistry. As scientists continue to investigate its properties and applications, it may pave the way for innovative treatments and advancements in pharmaceutical science.

Synonyms
m-Tolylhydrazide of diethylglycolic acid
Diethylglycolic acid m-tolylhydrazide
BRN 0650397
3166-51-6
Glycolic acid, diethyl-, m-tolylhydrazide
2-Ethyl-2-hydroxybutyric acid 2-(m-tolyl)hydrazide
DTXSID30185556
Butanoic acid, 2-ethyl-2-hydroxy-, 2-(3-methylphenyl)hydrazide
BUTYRIC ACID, 2-ETHYL-2-HYDROXY-, 2-(m-TOLYL)HYDRAZIDE
DTXCID70108047
Butanoic acid, 2-ethyl-2-hydroxy-, 2-(3-methylphenyl)hydrazide (9CI)