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2-ethyl-2-hydroxy-N'-(p-tolyl)butanehydrazide

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Identification
Molecular formula
C13H20N2O2
CAS number
68333-86-2
IUPAC name
2-ethyl-2-hydroxy-N'-(p-tolyl)butanehydrazide
State
State

The compound is a solid at room temperature, often taking the form of a powder or crystallized solid.

Melting point (Celsius)
150.00
Melting point (Kelvin)
423.15
Boiling point (Celsius)
385.00
Boiling point (Kelvin)
658.15
General information
Molecular weight
222.30g/mol
Molar mass
222.3030g/mol
Density
1.1560g/cm3
Appearence

The compound is typically a solid form at room temperature and can appear slightly yellow or white in color. It may also crystallize in fine needles or powder form, depending on the conditions under which it is prepared or stored.

Comment on solubility

Solubility of 2-ethyl-2-hydroxy-N'-(p-tolyl)butanehydrazide

The solubility of 2-ethyl-2-hydroxy-N'-(p-tolyl)butanehydrazide can be influenced by several factors, including its molecular structure and intermolecular interactions. This compound belongs to the hydrazide family, which typically displays varied solubility profiles based on the substituents present on the hydrazide group.

Factors Affecting Solubility:

  • Polarity: The presence of the hydroxyl (-OH) group in the structure enhances the polarity, which may lead to improved solubility in polar solvents such as water.
  • Hydrophobic Interactions: The p-tolyl group introduces hydrophobic characteristics, which may hinder solubility in highly polar solvents but improve solubility in organic solvents.
  • Temperature: Like many organic compounds, solubility tends to increase with temperature, allowing for greater interactions with solvent molecules.

In summary, the solubility of 2-ethyl-2-hydroxy-N'-(p-tolyl)butanehydrazide is a complex interplay of its structural traits and the solvent environment. Therefore, when exploring its solubility, one may consider:

  1. Testing in various solvents (e.g., water, ethanol, and acetone) to gauge comparative solubilities.
  2. Evaluating the effect of temperature and pressure on solubility behavior.

As always, a detailed experimental approach is recommended to ascertain precise solubility characteristics of this compound.

Interesting facts

Interesting Facts about 2-Ethyl-2-Hydroxy-N'-(p-Tolyl)butanehydrazide

2-Ethyl-2-hydroxy-N'-(p-tolyl)butanehydrazide is a fascinating chemical compound with various applications in organic chemistry and medicinal research. Here are some key points to consider:

  • Reactivity: This compound features a hydrazide functional group, which makes it particularly reactive with various electrophiles and nucleophiles. This enhances its utility in synthetic organic chemistry.
  • Biological Activity: Hydrazides, including this one, have been studied for their potential biological activity. Some hydrazide derivatives exhibit antibacterial and antitumor properties, making them valuable in pharmaceuticals.
  • Synthesis: The synthesis of this compound often involves the reaction of hydrazine derivatives with carbonyl compounds. Understanding these synthetic pathways is essential for chemists looking to create derivatives with modified properties.
  • Functionalization: The presence of both ethyl and p-tolyl groups in its structure allows for further functionalization. This means that chemists can modify the compound to enhance its properties or create novel materials.
  • Research Potential: Due to its complex structure, 2-ethyl-2-hydroxy-N'-(p-tolyl)butanehydrazide serves as a subject of interest for researchers investigating structure-activity relationships in drug design.

In summary, 2-ethyl-2-hydroxy-N'-(p-tolyl)butanehydrazide stands as a noteworthy compound not just for its chemical structure, but also for its potential applications in various fields of chemistry and biology. As scientists continue to explore its properties, it may pave the way for the development of new therapeutic agents.

Synonyms
Diethylglycolic acid p-tolylhydrazide
p-Tolylhydrazide of diethylglycolic acid
BRN 0747200
Glycolic acid, diethyl-, p-tolylhydrazide
3166-52-7
2-Ethyl-2-hydroxybutyric acid 2-(p-tolyl)hydrazide
DTXSID90185557
Butanoic acid, 2-ethyl-2-hydroxy-, 2-(4-methylphenyl)hydrazide
BUTYRIC ACID, 2-ETHYL-2-HYDROXY-, 2-(p-TOLYL)HYDRAZIDE
DTXCID30108048
Butanoic acid, 2-ethyl-2-hydroxy-, 2-(4-methylphenyl)hydrazide (9CI)
2-ethyl-2-hydroxy-N'-(4-methylphenyl)butanehydrazide
SCHEMBL8300053
STL326996
AKOS022131097