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2-Ethyl-2-phenylpropanediamide

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Identification
Molecular formula
C11H16N2O2
CAS number
.
IUPAC name
2-ethyl-2-phenyl-propanediamide
State
State

At room temperature, 2-ethyl-2-phenylpropanediamide is in a solid state. It is stable under standard conditions and must be handled with caution to avoid decomposition.

Melting point (Celsius)
216.00
Melting point (Kelvin)
489.15
Boiling point (Celsius)
355.00
Boiling point (Kelvin)
628.15
General information
Molecular weight
192.24g/mol
Molar mass
192.2420g/mol
Density
1.1000g/cm3
Appearence

2-Ethyl-2-phenylpropanediamide is typically a white or off-white crystalline solid. It may exhibit a powdery texture depending on the synthesis method and purity level. The compound is generally odorless.

Comment on solubility

Solubility of 2-ethyl-2-phenyl-propanediamide

2-ethyl-2-phenyl-propanediamide, often known for its role in various chemical applications, has unique **solubility characteristics** that are essential to understand. Its solubility can be influenced by several factors:

  • Polarity: This compound is moderately polar due to the presence of amide functional groups, which can interact with polar solvents.
  • Solvent Type: In general, 2-ethyl-2-phenyl-propanediamide tends to be more soluble in polar solvents such as water and alcohols compared to non-polar solvents.
  • Temperature: Increasing temperature can enhance solubility, allowing for better interaction between solute and solvent molecules.

As a result, one might find that:

  • In water, the solubility is moderate.
  • In ethanol, it exhibits improved solubility.
  • In hexane, the solubility may be quite low.

In summary, understanding the solubility of 2-ethyl-2-phenyl-propanediamide is critical for its effective use in various applications, especially where solvent interactions play a pivotal role. As the adage goes, "like dissolves like," which is particularly relevant in predicting the solubility of this compound in different media!

Interesting facts

Interesting Facts about 2-ethyl-2-phenyl-propanediamide

2-ethyl-2-phenyl-propanediamide, often encountered in various chemical syntheses, is a fascinating compound with distinct properties and applications. Here are some intriguing aspects to consider:

  • Amide Formation: This compound belongs to the class of amides, which are crucial in the formation of proteins and peptides. Amides are characterized by the functional group that consists of a carbonyl group (C=O) directly attached to a nitrogen atom (N).
  • Applications in Organic Synthesis: 2-ethyl-2-phenyl-propanediamide is utilized in multiple synthetic pathways. Its structure makes it an advantageous intermediate in the fabrication of pharmaceuticals and agrochemicals.
  • Reactivity: The presence of both amine and carbonyl groups contributes to the reactivity of the compound. This characteristic can be harnessed in various chemical reactions, allowing chemists to manipulate its structure for desired outcomes.
  • Chirality: The compound exhibits chirality due to the presence of chiral centers. This aspect is significant in the field of stereochemistry and has implications for biological activity, particularly in drug design.
  • Research and Development: Current studies continue to explore the potential of this compound as a precursor for novel materials or as part of more complex organic compounds.

The versatility of 2-ethyl-2-phenyl-propanediamide makes it a subject of interest not only for seasoned chemists but also for students keen to understand the interplay between structure and function in organic chemistry. As noted by prominent researchers, "The structure of a compound holds the key to its destiny in various chemical applications." This compound exemplifies that statement in every sense!

Synonyms
Phenylethylmalonamide
7206-76-0
2-ETHYL-2-PHENYLPROPANEDIAMIDE
2-Phenyl-2-ethylmalondiamide
Propanediamide, 2-ethyl-2-phenyl-
2-ethyl-2-phenyl-propanediamide
EINECS 230-583-9
UNII-67CFD7341W
BRN 1966103
CCRIS 4700
67CFD7341W
DTXSID3025885
2-Ethyl-2-phenylmalonic diamide
JFZHPFOXAAIUMB-UHFFFAOYSA-
4-09-00-03386 (Beilstein Handbook Reference)
PHENYL-2-ETHYLMALONDIAMIDE, 2-
PRIMIDONE IMPURITY A [EP IMPURITY]
Ethylphenylmalonamide
PRIMIDONE IMPURITY A (EP IMPURITY)
2 Ethyl 2 Phenylmalonamide
DTXCID505885
230-583-9
inchi=1/c11h14n2o2/c1-2-11(9(12)14,10(13)15)8-6-4-3-5-7-8/h3-7h,2h2,1h3,(h2,12,14)(h2,13,15)
jfzhpfoxaaiumb-uhfffaoysa-n
2-Ethyl-2-phenylmalonamide
PEMA
Phenylethylmalondiamide
PEMA (amide)
Malonamide, 2-ethyl-2-phenyl-
Propanediamide,2-ethyl-2-phenyl-
2-Ethyl-2-phenylmalondiamide
2-Phenyl-2-ethylmalonamide
80147-40-6
Ethylphenylmalondiamide
CHEBI:8097
PEMA-d5
4-Hydroxybenzenesulfonic Acid (85%)
4-Hydroxyphenylsulfonic acid; 4-Phenolsulfonic acid; NSC 227908; p-Hydroxybenzenesulfonic acid; p-Phenolsulfonic acid; p-Sulfophenol
phenyl-ethylmalonamide
Oprea1_383473
Phenylethylmalonamide (PEMA)
SCHEMBL341785
CHEMBL249467
STL415949
AKOS024284175
FE23105
NS00009497
C07499
A837408
Q3742460
2-Ethyl-2-phenyl-propanediamide;2-Ethyl-2-phenylmalondiamide;Phenylethylmalonamide