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Lenvatinib

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Identification
Molecular formula
C21H19ClN4O4
CAS number
417716-92-8
IUPAC name
2-ethyl-3-[4-[2-(1-piperidyl)ethoxy]anilino]isoindolin-1-one
State
State

At room temperature, Lenvatinib is typically in a solid state.

Melting point (Celsius)
260.00
Melting point (Kelvin)
533.15
Boiling point (Celsius)
505.90
Boiling point (Kelvin)
779.05
General information
Molecular weight
426.46g/mol
Molar mass
426.4550g/mol
Density
1.0608g/cm3
Appearence

Lenvatinib appears as a white to pale yellow powder. The compound is typically supplied as a fine powder for use in scientific and pharmaceutical applications.

Comment on solubility

Solubility Information for 2-ethyl-3-[4-[2-(1-piperidyl)ethoxy]anilino]isoindolin-1-one

The solubility of the compound 2-ethyl-3-[4-[2-(1-piperidyl)ethoxy]anilino]isoindolin-1-one (C21H19ClN4O4) is subject to various influencing factors, primarily governed by its structure and functional groups. Understanding these parameters can provide insight into its behavior in different solvents. Here are some key points regarding its solubility:

  • Polarity: The presence of multiple polar functional groups such as the ethoxy and piperidyl can enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The potential for hydrogen bonding with water molecules may increase solubility, impacting how this compound interacts with various solvents.
  • Log P Values: The log partition coefficient (Log P) can indicate whether the compound is more soluble in lipophilic (fat-soluble) or hydrophilic (water-soluble) environments. For this compound, a balance between hydrophilicity and lipophilicity is expected.

It is important to note that:

  1. High molecular weight can often correlate with lower solubility due to steric hindrance.
  2. Salts or derivatives may exhibit altered solubility characteristics compared to their neutral forms.

In summary, while 2-ethyl-3-[4-[2-(1-piperidyl)ethoxy]anilino]isoindolin-1-one has potential for solubility in certain solvents, the precise solubility behavior would require empirical measurement to definitively characterize it. As with many chemical compounds, context is crucial to understanding solubility and its implications in practical applications.

Interesting facts

Interesting Facts about 2-ethyl-3-[4-[2-(1-piperidyl)ethoxy]anilino]isoindolin-1-one

This intriguing compound belongs to a class of molecules known for their potential therapeutic applications. As a chemistry enthusiast or a budding scientist, you might appreciate the following insights:

  • Pharmacological Relevance: This structure suggests a role in medicinal chemistry, particularly in the development of pharmaceuticals. Compounds with similar structures have been studied for their anti-cancer properties.
  • Complexity of Structure: The presence of the isoindole moiety indicates a rich tapestry of reactivity and interaction possibilities within biological systems. Complex structures like this one often exhibit unique biological behavior due to their 3-dimensional shapes.
  • Substituent Effect: The 2-ethyl and 1-piperidyl groups provide specific steric and electronic properties that can significantly influence the compound's biological activity, making these functional groups a focal point during drug design.
  • Applications in Research: Compounds like this one are often used in various studies, including receptor binding assays and enzyme inhibition research. They can yield valuable data regarding the biochemical mechanisms of action involved in disease processes.
  • Development and Synthesis: Understanding how to synthesize such complex molecules is a great challenge for chemists! Each step in the synthesis process requires careful planning and a deep understanding of organic reactions.

As you explore the world of chemical compounds, you may find that the intricate details of structures such as 2-ethyl-3-[4-[2-(1-piperidyl)ethoxy]anilino]isoindolin-1-one open doors to exciting areas of research and innovation. Remember, understanding the structure is key to unlocking the function!

Synonyms
etomidoline
Amidoline
Smedolin
21590-92-1
Nonspa
Etomidolina
WFS7G78GYJ
DTXSID4048800
Amidoline; K 2680; Nonspa; Smedolin
2-ethyl-3-[4-(2-piperidin-1-ylethoxy)anilino]-3H-isoindol-1-one
K-2680
1H-Isoindol-1-one, 2-ethyl-2,3-dihydro-3-((4-(2-(1-piperidinyl)ethoxy)phenyl)amino)-
2-Ethyl-2,3-dihydro-3-((4-(2-(1-piperidinyl)ethoxy)phenyl)amino)-1H-isoindol-1-one
Etomidolinum
Smedolin (TN)
Etomidoline (JAN/INN)
Etomidoline [INN:JAN]
ETOMIDOLINE [MI]
UNII-WFS7G78GYJ
ETOMIDOLINE [INN]
ETOMIDOLINE [JAN]
Etomidolinum [INN-Latin]
Etomidolina [INN-Spanish]
K 2680
ETOMIDOLINE [MART.]
ETOMIDOLINE [WHO-DD]
SCHEMBL249757
CHEMBL2106603
DTXCID7028726
CHEBI:31584
ITIONVBQFUNVJV-UHFFFAOYSA-N
EINECS 244-463-9
Tox21_113277
AKOS040751748
CAS-21590-92-1
NS00050324
D01359
Q27292615
2-Ethyl-3-(beta-piperidino-p-phenetidino)phthalimidine
Phthalimidine, 2-ethyl-3-(beta-piperidino-p-phenetidino)-
2-ETHYL-3-(.BETA.-PIPERIDINO-P-PHENETIDINO)PHTHALIMIDINE
2-Ethyl-3-(p-(beta-piperidinoethoxy)phenylamino)-isoindoline-1-one