Skip to main content

2-Ethyl-3,4-dihydro-1H-isoquinolin-5-ol

ADVERTISEMENT
Identification
Molecular formula
C11H15NO
CAS number
173878-01-8
IUPAC name
2-ethyl-3,4-dihydro-1H-isoquinolin-5-ol
State
State

At room temperature, 2-Ethyl-3,4-dihydro-1H-isoquinolin-5-ol is in a solid state. It typically appears as a powder or fine crystals.

Melting point (Celsius)
112.00
Melting point (Kelvin)
385.15
Boiling point (Celsius)
282.00
Boiling point (Kelvin)
555.15
General information
Molecular weight
175.24g/mol
Molar mass
175.2350g/mol
Density
1.1345g/cm3
Appearence

2-Ethyl-3,4-dihydro-1H-isoquinolin-5-ol typically presents as a white to off-white crystalline solid. The substance tends to form well-defined crystals and is usually in powder form, which can be sensitive to light and moisture.

Comment on solubility

Solubility of 2-ethyl-3,4-dihydro-1H-isoquinolin-5-ol

The solubility of 2-ethyl-3,4-dihydro-1H-isoquinolin-5-ol is influenced by various factors including its chemical structure and interactions with solvents. This compound exhibits moderate solubility in polar solvents due to its hydroxyl (-OH) group, which is capable of forming hydrogen bonds.

Solubility Characteristics:

  • Polar Solvents: Generally, 2-ethyl-3,4-dihydro-1H-isoquinolin-5-ol displays good solubility in water and alcohols such as methanol and ethanol.
  • Non-Polar Solvents: The solubility decreases significantly in non-polar organic solvents like hexane or toluene, due to the lack of hydrogen bonding capabilities.
  • Temperature Dependency: Solubility can increase with temperature, making it more soluble in warm solvents.

Overall, when considering dissolution, it is crucial to reflect on the interactions between the compound's functional groups and the solvent. As a rule of thumb in chemistry, "like dissolves like," indicating that polar solutes generally dissolve well in polar solvents. Therefore, the presence of the hydroxyl group in 2-ethyl-3,4-dihydro-1H-isoquinolin-5-ol favors its solubility in aqueous environments and other polar media.

Interesting facts

Interesting Facts about 2-Ethyl-3,4-dihydro-1H-isoquinolin-5-ol

2-Ethyl-3,4-dihydro-1H-isoquinolin-5-ol is a fascinating organic compound that belongs to the isoquinoline family, known for its diverse biological activity and significance in medicinal chemistry. Here are some noteworthy aspects of this compound:

  • Structural Versatility: The structure of this compound features a fused bicyclic system, which is characteristic of isoquinolines. This configuration opens up a range of synthetic pathways and potential derivatives for pharmacological applications.
  • Biological Activity: Isoquinoline derivatives are implicated in various biological processes. They can exhibit a range of activities, including but not limited to analgesic, antitumor, and antimalarial effects. Therefore, 2-ethyl-3,4-dihydro-1H-isoquinolin-5-ol could serve as a lead compound for developing novel therapeutics.
  • Research Interest: Researchers are continually exploring its potential as a core structure for drug development, especially in the field of neurology and cancer therapy.
  • Natural Occurrences: Compounds similarly structured to 2-ethyl-3,4-dihydro-1H-isoquinolin-5-ol can be found in a variety of natural sources, such as plants and fungi, further emphasizing their significance in biochemistry and natural product chemistry.
  • Chirality and Optics: Depending on its stereochemistry, this compound may exhibit chiral properties, which is critical for pharmacodynamics. The optical activity of such compounds can influence their biological interactions.

In summary, 2-ethyl-3,4-dihydro-1H-isoquinolin-5-ol is not just a simple chemical compound; it embodies a world of potential applications and research avenues in medicinal chemistry. As scientists continue to unlock its mysteries, who knows what therapeutic wonders await us in the future?

Synonyms
16232-60-3
SCHEMBL21216375
DB-409636
2-Ethyl-1,2,3,4-tetrahydro-5-isoquinolinol