(2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate

Identification

Molecular formula

C₁₄H₁₉NO₂

CAS number

127718-71-2

IUPAC name

(2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate

State

At room temperature, this compound is typically a solid. It may manifest as a powder or small crystalline forms, suitable for various organic synthesis applications.

Melting point (Celsius)

150.00

Melting point (Kelvin)

423.15

Boiling point (Celsius)

382.00

Boiling point (Kelvin)

655.15

General information

Molecular weight

233.31g/mol

Molar mass

233.2990g/mol

Density

1.1520g/cm³

Appearence

The compound appears as a white to off-white solid. It typically may exist in the form of crystalline powder and can be sublimable. Some compounds in this class are known for their characteristic odor, but specific sensory properties can vary.

Comment on solubility

Solubility of (2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate

(2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate, often referred to in its abbreviated forms, presents some fascinating characteristics regarding its solubility in various solvents. Understanding the solubility of this compound is crucial for its applications in both industrial and laboratory settings.

Key points about its solubility include:

Polar Solvents: This compound is expected to have moderate solubility in polar solvents like water due to the presence of the acetate group, which can engage in hydrogen bonding.
Non-Polar Solvents: Conversely, it is likely to show higher solubility in non-polar organic solvents such as chloroform and hexane because of its hydrophobic isoquinoline structure.
Temperature Effects: Temperature can significantly affect solubility; increased temperature typically enhances solubility in most liquids.
Concentration Provisions: When preparing solutions, consider that higher concentrations might lead to reduced solubility, especially in water.

In summary, the solubility of (2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate is a complex interplay of structural factors, solvent characteristics, and environmental conditions. As emphasized in various studies, "like dissolves like," which underscores the importance of choosing the correct solvent for achieving optimal solubility.

Interesting facts

Interesting Facts about (2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate

The compound (2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate is a fascinating member of the isoquinoline family. Here's why it stands out:

Biological Activity: Compounds derived from isoquinoline often exhibit a variety of biological activities. For instance, some studies suggest that they can function as anti-cancer and antimicrobial agents, potentially opening new avenues for drug development.
Chemical Structure: The unique polycyclic structure of isoquinolines contributes to their diverse chemical reactivity, making them valuable in organic synthesis and the development of pharmaceuticals.
Synthetic Pathways: One noteworthy aspect of this compound is the diversity of synthetic methods available for its preparation. Researchers can utilize various techniques to incorporate the acetate group and achieve the desired alkylation.
Natural Occurrences: Isoquinoline alkaloids, a class that includes this compound, are found in numerous plant species, thereby highlighting their significance in natural product chemistry.
Potential Applications: Beyond medicinal chemistry, compounds like (2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate can also be explored for use in agrochemicals and material science due to their unique properties.

In the words of a renowned chemist, “The beauty of organic chemistry lies in the intricate dance between structure and function.” This compound exemplifies that dance and showcases the potential for discovery that lies within each molecular framework.

Overall, (2-ethyl-3,4-dihydro-1H-isoquinolin-5-yl) acetate not only expands our understanding of isoquinoline chemistry but also inspires further research into its practical applications.