2-ethyl-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-5-ol

Identification

Molecular formula

C₁₁H₂₁NO

CAS number

72570-80-8

IUPAC name

2-ethyl-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-5-ol

State

At room temperature, 2-ethyl-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-5-ol can be found as a solid or a liquid depending on its purity. It solidifies just above room temperature and can melt easily back into a liquid form when slightly warmed.

Melting point (Celsius)

32.00

Melting point (Kelvin)

305.15

Boiling point (Celsius)

292.50

Boiling point (Kelvin)

565.65

General information

Molecular weight

181.27g/mol

Molar mass

181.2730g/mol

Density

1.1310g/cm³

Appearence

This compound typically appears as a colorless to pale yellow liquid or crystalline solid, depending on its specific form and purity. It may have a distinct chemical odor and is generally known for its optical activity.

Comment on solubility

Solubility of 2-ethyl-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-5-ol

The solubility of 2-ethyl-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-5-ol is an intriguing aspect of this compound. Understanding its behavior in various solvents helps in predicting its interactions and applications in chemical and pharmaceutical contexts. Here are some key points to consider:

Polyhydroxy Functionality: The presence of a hydroxyl (-OH) group typically increases solubility in polar solvents like water.
Hydrophobic Alkyl Chain: The 2-ethyl substituent contributes hydrophobic characteristics, which could decrease solubility in polar environments.
Solvent Effects: Solubility is often enhanced in organic solvents such as ethanol or dimethyl sulfoxide (DMSO) due to their ability to interact with both hydrophobic and polar regions of the molecule.
pH Dependence: The ionization of the hydroxyl group can also affect solubility depending on the pH of the solution.

In summary, while the solubility of this compound is subject to variability influenced by multiple factors, its unique structural features provide insight into its potential behavior in different environments. As with many organic compounds, experimental determination is essential for precise solubility insights.

Interesting facts

Interesting Facts about 2-ethyl-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-5-ol

The compound known as 2-ethyl-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-5-ol is part of a fascinating class of organic compounds called isoquinolines, which are often studied for their diverse biological activities. Here are some compelling facts about this intriguing compound:

Structural Characteristics: The structure of this compound features a multi-cyclic framework that is rich in hydrogen atoms, which contributes to its stability and reactivity.
Potential Pharmacological Uses: Isoquinoline derivatives are known for their potential therapeutic effects. This compound may exhibit activity in neuroprotection and could be explored for its benefits in treating neurological disorders.
Natural Occurrence: Many isoquinolines can be found in nature, especially in alkaloids derived from various plants. This compound’s structural similarity to naturally occurring substances can provide insights into natural product synthesis.
Synthetic Versatility: The synthesis of this compound can be achieved through various methods, highlighting its versatility in organic chemistry and the potential application in creating complex molecular structures.

Scientists continue to be intrigued by isoquinoline compounds like 2-ethyl-3,4,4a,5,6,7,8,8a-octahydro-1H-isoquinolin-5-ol due to their significant roles in medicinal chemistry and their importance in understanding biological systems. The exploration of such compounds not only contributes to advancing pharmaceutical applications but also deepens our understanding of organic synthesis and reaction mechanisms.

In conclusion, the study of this compound opens up a realm of possibilities in both theoretical and applied chemistry, making it a noteworthy subject for researchers and students alike.