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2-Ethyl-4-methylpyridine

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Identification
Molecular formula
C8H11N
CAS number
2344-28-1
IUPAC name
2-ethyl-4-methyl-pyridine;3-ethyl-2-methyl-pyridine;4-ethyl-3-methyl-pyridine
State
State

This compound exists as a liquid at room temperature.

Melting point (Celsius)
-52.90
Melting point (Kelvin)
220.30
Boiling point (Celsius)
180.60
Boiling point (Kelvin)
453.80
General information
Molecular weight
121.18g/mol
Molar mass
121.1800g/mol
Density
0.9042g/cm3
Appearence

2-Ethyl-4-methylpyridine is a colorless liquid with a characteristic pyridine-like odor. It is miscible with most organic solvents but only slightly soluble in water.

Comment on solubility

Solubility of 2-ethyl-4-methyl-pyridine, 3-ethyl-2-methyl-pyridine, and 4-ethyl-3-methyl-pyridine

The solubility of the pyridine derivatives, namely 2-ethyl-4-methyl-pyridine, 3-ethyl-2-methyl-pyridine, and 4-ethyl-3-methyl-pyridine, presents interesting characteristics due to their distinct molecular structures. Here are some key points to consider:

  • Polar Nature: These compounds exhibit moderate polarity due to their nitrogen atom, which can engage in hydrogen bonding. This feature generally enhances their solubility in polar solvents like water.
  • Hydrophobic Interactions: The ethyl and methyl groups contribute to hydrophobic characteristics, which can reduce solubility in highly polar solvents.
  • Temperature Dependence: The solubility of these compounds can significantly vary with temperature. Typically, higher temperatures increase solubility due to enhanced molecular movement.
  • Solvent Compatibility: The solubility behavior tends to align favorably with organic solvents such as ethanol or acetone, where their lipophilic nature complements the solvent properties.
  • Concentration Effects: At higher concentrations, the presence of these compounds in a solution may lead to saturation points where solubility limits are reached.

In conclusion, while the solubility of 2-ethyl-4-methyl-pyridine, 3-ethyl-2-methyl-pyridine, and 4-ethyl-3-methyl-pyridine may not exhibit extreme behavior, understanding their balance of hydrophilic and hydrophobic interactions provides insight into their behavior in various solvents. Keep in mind that the specific solubility values can be significantly influenced by environmental factors and solvent choice.

Interesting facts

Interesting Facts about 2-Ethyl-4-methyl-pyridine, 3-Ethyl-2-methyl-pyridine, and 4-Ethyl-3-methyl-pyridine

The compounds 2-ethyl-4-methyl-pyridine, 3-ethyl-2-methyl-pyridine, and 4-ethyl-3-methyl-pyridine are isomeric alkyl-substituted pyridines, which means they share the same molecular formula yet possess different structural arrangements. These variations lead to unique properties and potential applications for each isomer. Here are some interesting insights:

  • Structural Diversity: The different positions of the ethyl and methyl groups on the pyridine ring allow for various electronic and steric interactions, leading to distinct behavior in chemical reactions.
  • Applications in Pharmaceuticals: Many substituted pyridines, including these isomers, are found in pharmaceuticals as they can enhance biological activity or function as precursors in drug synthesis.
  • Role in Organic Synthesis: These compounds are significant intermediates in organic synthesis, frequently utilized in the production of dyes, agrochemicals, and other fine chemicals.
  • Characteristically Aromatic: All three compounds retain the aromatic nature of the pyridine ring, contributing to stability and enabling diverse reactivity in electrophilic substitutions.
  • Flavor and Fragrance: Some alkyl-pyridine compounds are known for their distinct odors, which can be harnessed in the flavor and fragrance industry.

In summary, the 2-ethyl-4-methyl-pyridine, 3-ethyl-2-methyl-pyridine, and 4-ethyl-3-methyl-pyridine showcase how small changes in molecular structure can lead to significant implications in chemistry and industry. As stated by a renowned chemist, "Understanding the nuances of molecular arrangement is key to unlocking the full potential of chemical compounds." This emphasizes the importance of these isomers in both academic research and practical applications.