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Lidocaine

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Identification
Molecular formula
C14H22N2O
CAS number
137-58-6
IUPAC name
2-[ethyl(2-methoxyethyl)amino]-N-(2,4,6-trimethylphenyl)acetamide
State
State

At room temperature, lidocaine is a solid. In its pure form, it is typically found as a powder, but it may also be found in various formulated states such as gels, solutions, or lotions, depending on its specific application.

Melting point (Celsius)
66.00
Melting point (Kelvin)
339.15
Boiling point (Celsius)
350.00
Boiling point (Kelvin)
623.15
General information
Molecular weight
234.34g/mol
Molar mass
234.3370g/mol
Density
1.0260g/cm3
Appearence

Lidocaine appears as a white crystalline powder and is odorless. It is sparingly soluble in water and soluble in alcohol and chloroform.

Comment on solubility

Solubility of 2-[ethyl(2-methoxyethyl)amino]-N-(2,4,6-trimethylphenyl)acetamide

The solubility of 2-[ethyl(2-methoxyethyl)amino]-N-(2,4,6-trimethylphenyl)acetamide in various solvents provides interesting insights into its chemical behavior. This compound, characterized by its complex structure, exhibits unique solubility properties.

Key Factors Influencing Solubility:

  • Polarity: Due to the presence of both hydrophilic and hydrophobic groups, the solubility is influenced by the polarity of the solvent.
  • Temperature: Like many organic compounds, its solubility can increase with temperature, which is an important consideration in practical applications.
  • Presence of Functional Groups: The methoxy and amine functional groups play a crucial role in solubilizing the compound in polar solvents.

In general, this compound is expected to be more soluble in polar organic solvents, such as:

  • Dimethyl sulfoxide (DMSO)
  • Acetone
  • Ethanol

Conversely, it may have limited solubility in non-polar solvents such as hexane or toluene due to its polar characteristics. As a result, understanding these solubility parameters is vital for applications in drug formulation and chemical processing.

Ultimately, *the solubility of 2-[ethyl(2-methoxyethyl)amino]-N-(2,4,6-trimethylphenyl)acetamide can significantly affect its bioavailability and efficacy in various pharmaceutical contexts*.

Interesting facts

Interesting Facts about 2-[ethyl(2-methoxyethyl)amino]-N-(2,4,6-trimethylphenyl)acetamide

This compound is part of a class of chemicals known as acetanilides, which have garnered significant attention in both the pharmaceutical and chemical industries. Notably, their unique structure allows for diverse applications, particularly in medicinal chemistry.

Applications and Uses

  • Pharmaceutical Development: Its structure provides potential as a scaffold in drug design, leading to possible innovations in therapeutic agents.
  • Research: Scientists study such compounds to understand their interactions at a molecular level, contributing to the development of more effective drugs.
  • Targeting Mechanisms: The presence of the 2,4,6-trimethylphenyl group can influence the compound's ability to bind to biological receptors or enzymes, a critical factor in drug efficacy.

Molecular Features

Understanding the molecular features can help in predicting the behavior of this compound:

  • Amine Group: The ethyl(2-methoxyethyl)amino portion of the structure may enhance solubility and biological activity.
  • Electrophilic centers: Reactivity and interaction potentials can be attributed to the various substituents present in the molecule.

Scientific Perspective

From a scientific perspective, the synthesis and modification of such compounds can lead to:

  • Improved understanding of structure-activity relationships (SAR).
  • Opportunities for creating more targeted and safer therapeutic solutions.
  • Inspiration for novel methods in organic synthesis.

Overall, the study of 2-[ethyl(2-methoxyethyl)amino]-N-(2,4,6-trimethylphenyl)acetamide opens up avenues for exciting research in organic and medicinal chemistry, showcasing the intricate connection between molecular design and biological function.

Synonyms
BRN 2986983
22164-95-0
ACETANILIDE, 2-(ETHYL(2-METHOXYETHYL)AMINO)-2',4',6'-TRIMETHYL-
2-(N-Ethyl-2-methoxyethylamino)-2',4',6'-trimethylacetanilide
DTXSID80176696
RefChem:315728
DTXCID7099187