2-(ethylamino)-1-(3-fluorophenyl)ethanol

Identification

Molecular formula

C₁₀H₁₄FNO

CAS number

56776-36-2

IUPAC name

2-(ethylamino)-1-(3-fluorophenyl)ethanol

State

At room temperature, 2-(ethylamino)-1-(3-fluorophenyl)ethanol is in a solid state.

Melting point (Celsius)

70.00

Melting point (Kelvin)

343.15

Boiling point (Celsius)

305.30

Boiling point (Kelvin)

578.45

General information

Molecular weight

183.23g/mol

Molar mass

183.2270g/mol

Density

1.1620g/cm³

Appearence

2-(Ethylamino)-1-(3-fluorophenyl)ethanol typically appears as a solid. This compound can be found in the form of a powder, and it is often white to off-white in color. It does not have a distinctive odor.

Comment on solubility

Solubility of 2-(ethylamino)-1-(3-fluorophenyl)ethanol

The solubility of 2-(ethylamino)-1-(3-fluorophenyl)ethanol can be influenced by several factors due to its unique chemical structure. This compound, characterized by both hydrophilic (water-attracting) and hydrophobic (water-repelling) groups, generally exhibits moderate to high solubility in aqueous solutions, primarily depending on the pH of the environment.

Key points regarding its solubility include:

Hydrophilicity: The presence of the ethylamino group contributes to a tendency towards solvation in polar solvents, notably water.
Hydrophobic Characteristics: The 3-fluorophenyl group introduces hydrophobic properties, which can hinder solubility in pure water.
Effect of pH: The solubility may significantly increase in acidic conditions due to protonation of the amine, enhancing interaction with water molecules.

As a result, when considering its application or behavior in different environments:

In neutral aqueous solutions, the solubility is likely adequate for biological and chemical processes.
Under basic conditions, solubility might decrease as the compound could revert to its less soluble form.

In summary, while 2-(ethylamino)-1-(3-fluorophenyl)ethanol is generally soluble in water, its effective solubility can be dramatically altered by environmental conditions and pH levels, making it important to consider these factors in practical applications.

Interesting facts

Interesting Facts About 2-(ethylamino)-1-(3-fluorophenyl)ethanol

2-(ethylamino)-1-(3-fluorophenyl)ethanol is a fascinating compound that showcases the intricate relationships between molecular structure and biological activity. This compound belongs to the class of ethanolamines, which are known for their diverse applications in medicinal chemistry and pharmacology.

Key Aspects of 2-(ethylamino)-1-(3-fluorophenyl)ethanol:

Pharmacological Potential: The presence of a fluorine atom in the 3-position on the phenyl ring can significantly enhance the lipophilicity and metabolic stability of the compound, making it a candidate for various therapeutic roles.
Secondary Amine Functionality: The ethylamino group introduces a secondary amine, which can participate in hydrogen bonding and ionic interactions, crucial for binding affinity with biological targets such as receptors or enzymes.
Structure-Activity Relationship (SAR): The modification of both the amine and phenyl moieties offers valuable insights into how slight changes in chemical structure can affect the overall biological effect, guiding medicinal chemists in drug design.

Moreover, this compound poses interesting avenues for research into neurotransmitter systems, particularly as scientists explore compounds that may influence serotonin or norepinephrine pathways. Its potential also extends to exploring how such modifications could lead to improved efficacy or reduced side effects in pharmacological treatments.

As we delve deeper into the world of chemical compounds like 2-(ethylamino)-1-(3-fluorophenyl)ethanol, we remind ourselves of the profound impact that small changes at the molecular level can have. "Chemistry is the story of our lives," a saying that resonates deeply within the realm of chemical exploration and biomolecular research.