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Fluoxetine hydrobromide

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Identification
Molecular formula
C11H16FNO.HBr
CAS number
59333-67-4
IUPAC name
2-(ethylamino)-1-(3-fluorophenyl)ethanol;hydrobromide
State
State

At room temperature, fluoxetine hydrobromide is typically in a solid state.

Melting point (Celsius)
179.00
Melting point (Kelvin)
452.15
Boiling point (Celsius)
233.80
Boiling point (Kelvin)
507.00
General information
Molecular weight
297.26g/mol
Molar mass
297.2570g/mol
Density
1.2760g/cm3
Appearence

Fluoxetine hydrobromide typically appears as a white to off-white crystalline powder. It is odorless and has a slightly bitter taste.

Comment on solubility

Solubility of 2-(ethylamino)-1-(3-fluorophenyl)ethanol; hydrobromide

The solubility of a compound can often be a crucial factor influencing its utility and behavior in various chemical applications. In the case of 2-(ethylamino)-1-(3-fluorophenyl)ethanol; hydrobromide, several aspects contribute to understanding its solubility characteristics:

  • Polarity: The presence of both an amino group and a hydrobromide ion suggests a certain level of polarity, which may enhance solubility in polar solvents like water.
  • Hydrogen Bonding: The hydroxyl group and the amino group in the structure can participate in hydrogen bonding, promoting solubility in aqueous environments.
  • Ionic Nature: As a hydrobromide, the compound ionizes in solution, potentially increasing solubility in ionic solvents.

“Generally, compounds with ionic or polar functional groups tend to have higher solubility in polar solvents.” In contrast, the presence of a fluorine atom may have a nuanced effect on the overall stability of the solute in solution. Fluorine is known for its electronegativity and can influence the solubility through dipole interactions.

To summarize, the solubility of 2-(ethylamino)-1-(3-fluorophenyl)ethanol; hydrobromide can be anticipated to be favorable in polar solvents, primarily due to its ionic nature and ability to engage in hydrogen bonding, which often confers enhanced solubility properties in biological and chemical interactions.

Interesting facts

Interesting Facts about 2-(Ethylamino)-1-(3-fluorophenyl)ethanol; Hydrobromide

The compound 2-(ethylamino)-1-(3-fluorophenyl)ethanol; hydrobromide is a fascinating entity in the field of medicinal chemistry. This particular compound serves as a key intermediate in the synthesis of various pharmaceuticals, primarily due to its unique structural characteristics. Below are some engaging insights about this compound:

  • Pharmacological Relevance: The presence of the 3-fluorophenyl group enhances the compound's biological activity by modifying its interaction with certain receptors, making it a subject of interest for drug development.
  • Chemical Behavior: The ethylamino group contributes to the compound's ability to act as a weak base, which can significantly influence its solubility and reactivity in biological systems.
  • Hydrobromide Salt: The formation of the hydrobromide salt form increases its stability and can enhance its bioavailability, which is crucial for therapeutic applications.
  • Synthesis Pathway: Chemists often employ reductive amination methods to synthesize this compound, making it an interesting topic for students learning synthetic organic chemistry.
  • Potential Applications: Research indicates that compounds with similar structures may show promise in treating neurological disorders due to their effects on neurotransmitter systems.

This compound exemplifies the intricate relationship between molecular structure and pharmacological activity, providing a strong foundation for ongoing research and development in medicinal chemistry.

Synonyms
349-26-8
alpha-Ethylaminomethyl-3-fluorobenzyl alcohol hydrobromide
2-Ethylamino-1-(3-fluorophenyl)ethanol hydrobromide
Ethanol, 2-ethylamino-1-(3-fluorophenyl)-, hydrobromide
BENZYL ALCOHOL, alpha-ETHYLAMINOMETHYL-3-FLUORO-, HYDROBROMIDE
DTXSID40956375
2-(Ethylamino)-1-(3-fluorophenyl)ethan-1-ol--hydrogen bromide (1/1)