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Ketamine

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Identification
Molecular formula
C13H16ClNO
CAS number
6740-88-1
IUPAC name
2-(ethylamino)-2-(2-thienyl)cyclohexanone
State
State

At room temperature, ketamine is typically in a liquid form for medical usage, but it can also exist as a crystalline solid.

Melting point (Celsius)
258.00
Melting point (Kelvin)
531.15
Boiling point (Celsius)
205.00
Boiling point (Kelvin)
478.15
General information
Molecular weight
237.34g/mol
Molar mass
237.3410g/mol
Density
1.0460g/cm3
Appearence

Ketamine is typically a white crystalline powder. In its liquid form, it is a colorless, clear solution. When used as a pharmaceutical, it may also appear in tablet form.

Comment on solubility

Solubility of 2-(ethylamino)-2-(2-thienyl)cyclohexanone

The solubility of 2-(ethylamino)-2-(2-thienyl)cyclohexanone can be influenced by various factors, including temperature and the presence of different solvents. Here are some key points to consider:

  • Polar vs. Nonpolar Solvents: Due to its molecular structure, this compound may show greater solubility in polar solvents like water or alcohols, owing to the presence of the amino group which can interact favorably with polar solvents.
  • Hydrogen Bonding: The capacity of the amino group (-NH2) to form hydrogen bonds can enhance solubility in appropriate solvents while also affecting the overall stability of the compound in solution.
  • Temperature Dependence: As with many organic compounds, solubility can increase with temperature, allowing for more efficient dissolution of the compound in suitable solvents.
  • Functional Groups: The presence of the thienyl group in its structure may introduce specific interactions with solvents that can either promote or hinder solubility.

In conclusion, while the specific solubility data for 2-(ethylamino)-2-(2-thienyl)cyclohexanone may vary, understanding these factors is crucial for predicting its behavior in different environments. Always consider the solvent's polarity and the molecular interactions at play when assessing solubility.

Interesting facts

Interesting Facts About 2-(ethylamino)-2-(2-thienyl)cyclohexanone

2-(ethylamino)-2-(2-thienyl)cyclohexanone is a fascinating compound that belongs to the class of ketones and features unique structural properties. Here are some noteworthy points:

  • Structure and Composition: This compound contains a cyclohexanone structure, which is highly valued in organic synthesis due to its versatility. The presence of an ethylamino group enhances its reactivity, opening up potential avenues for further derivatization.
  • Thienyl Influence: The attached thienyl group contributes not only to the compound's chemical characteristics but also its biological activities. Thiophene derivatives are known for their interesting electronic properties, making this compound a subject of study in organic electronics and materials science.
  • Chemical Behavior: As a ketone, 2-(ethylamino)-2-(2-thienyl)cyclohexanone exhibits typical reactivity patterns such as nucleophilic additions. Its unique substituents may alter its reactivity in unexpected ways.
  • Potential Applications: Given its structural framework, researchers are investigating this compound for use in pharmaceuticals. Compounds with similar structures have been noted for their potential therapeutic effects, including anti-inflammatory and analgesic properties.
  • Interdisciplinary Relevance: This compound serves as a bridge between organic chemistry and medicinal chemistry, showcasing how understanding fundamental chemical structures can lead to innovative medical advancements.

In summary, 2-(ethylamino)-2-(2-thienyl)cyclohexanone stands out not only for its unique structural characteristics but also for its broader implications in chemical research and potential applications in various fields.

Synonyms
TILETAMINE
14176-49-9
Tiletamina
Cyclohexanone, 2-(ethylamino)-2-(2-thienyl)-
2-(Ethylamino)-2-(2-thienyl)cyclohexanone
Tiletaminum
2YFC543249
DTXSID5048552
DTXCID1028108
2-(Ethylamino)-2-(thiophen-2-yl)cyclohexan-1-one
238-031-9
2-(ethylamino)-2-thiophen-2-ylcyclohexan-1-one
14176-49-9 (free base)
Tiletamine (INN)
TILETAMINE [INN]
Tiletamine [INN:BAN]
Tiletaminum [INN-Latin]
Tiletamina [INN-Spanish]
EINECS 238-031-9
UNII-2YFC543249
HSDB 7638
TILETAMINE [MI]
Prestwick0_001022
Prestwick1_001022
Prestwick2_001022
Prestwick3_001022
TILETAMINE [HSDB]
TILETAMINE [WHO-DD]
BSPBio_001203
SCHEMBL115212
SPBio_003064
BPBio1_001325
CHEMBL2110703
CHEBI:94356
AKOS005066229
DB11549
NCGC00179264-01
NCGC00179264-03
AC-23715
DA-10477
AB00514642
NS00015413
2-(Ethylamino)-2-(2-thienyl)cyclohexanone #
D08596
2-(ethylamino)-2-thiophen-2-yl-1-cyclohexanone
AB00514642_02
2-(ethylamino)-2-thiophen-2-yl-cyclohexan-1-one
A807808
Q2083144
BRD-A30582499-003-01-0
BRD-A30582499-003-05-1