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N-Ethylphthalimide

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Identification
Molecular formula
C10H9NO2
CAS number
1841-30-3
IUPAC name
2-ethylisoindoline-1,3-dione
State
State

At room temperature, it is solid.

Melting point (Celsius)
75.00
Melting point (Kelvin)
348.15
Boiling point (Celsius)
376.00
Boiling point (Kelvin)
649.15
General information
Molecular weight
189.22g/mol
Molar mass
189.2190g/mol
Density
1.2195g/cm3
Appearence

The compound appears as a white to yellow crystalline solid.

Comment on solubility

Solubility of 2-ethylisoindoline-1,3-dione

2-ethylisoindoline-1,3-dione, a compound featuring a unique fused ring structure, exhibits notable solubility characteristics that are essential for its application in various chemical contexts.

Generally, its solubility can be influenced by several factors:

  • Polarity: The presence of polar and non-polar groups in the compound affects its solubility in different solvents. Compounds with polar groups may be more soluble in polar solvents like water, while non-polar solvents such as hexane can dissolve non-polar compounds effectively.
  • Temperature: Solubility often increases with temperature. For 2-ethylisoindoline-1,3-dione, testing its solubility at various temperatures can yield relevant insights into its behavior under different conditions.
  • pH Levels: The acidity or basicity of the solution can also have a significant impact on solubility, especially for compounds that can ionize.

In general, 2-ethylisoindoline-1,3-dione demonstrates better solubility in organic solvents compared to water due to its structural characteristics. It is commonly soluble in:

  • Dichloromethane
  • Chloroform
  • Acetone

However, like many diones, it may have limited solubility in alcohols and aqueous solutions. Understanding its solubility profile is crucial for its utilization in different chemical syntheses, as effective dissolution affects reaction kinetics and product isolation.

Ultimately, when working with 2-ethylisoindoline-1,3-dione, it is vital to consider the specific solubility parameters in relation to your experimental design to achieve the best results.

Interesting facts

Interesting Facts About 2-Ethylisoindoline-1,3-dione

2-Ethylisoindoline-1,3-dione is a fascinating compound that belongs to the family of isoindoline derivatives. These compounds have attracted considerable attention in recent years due to their unique structural properties and potential applications.

  • Structural Features: The structure of 2-ethylisoindoline-1,3-dione includes an isoindoline moiety, which contributes to its stability and reactivity. The presence of the ethyl group at the 2-position enhances its solubility and may influence its biological activities.
  • Biological Significance: Compounds like 2-ethylisoindoline-1,3-dione have been studied for their potential antimicrobial, anti-inflammatory, and even anticancer properties. This makes them of particular interest in medicinal chemistry.
  • Electron-Dense Environment: The presence of two carbonyl groups in the structure contributes to a rich electron-dense environment, which can facilitate various chemical reactions, including nucleophilic attacks and cycloadditions.
  • Synthetic Applications: The ability to synthesize derivatives of isoindoline-1,3-dione is valuable in creating new materials and pharmaceuticals. Chemists are continuously exploring different synthesis routes for functionalizing the isoindoline scaffold.
  • Fluorescent Properties: This compound has shown interesting fluorescent properties, making it beneficial in biological imaging and sensing applications, where visualization of cellular processes is essential.

In conclusion, 2-ethylisoindoline-1,3-dione is not just a simple compound; it stands as a testament to the intricate relationships between structure and function in chemistry. The ongoing research and exploration in the field may uncover even more exciting applications that harness its unique characteristics.

Synonyms
N-Ethylphthalimide
2-ethylisoindoline-1,3-dione
PHTHALIMIDE, N-ETHYL-
1H-Isoindole-1,3(2H)-dione, 2-ethyl-
1H-Isoindole-1,3(2H)-dione, N-ethyl-
2-Ethyl-1H-isoindole-1,3(2H)-dione
NSC 2774
EINECS 225-707-3
BRN 0132094
2PU4A53CO7
AI3-01394
NSC-2774
UNII-2PU4A53CO7
1H-Iosindole-1,3(2H)-dione, 2-ethyl-
DTXSID4052134
5-21-10-00274 (Beilstein Handbook Reference)
DTXCID9030703
1H-Iosindole-1,3(2H)-dione, 2-ethyl-(9CI)
1H-Isoindole-1,3(2H)-dione, N-ethyl-(9CI)
225-707-3
jzdsoqsucwvbmv-uhfffaoysa-n
5022-29-7
2-ethylisoindole-1,3-dione
2-ethyl-2,3-dihydro-1H-isoindole-1,3-dione
MFCD00014583
NSC2774
N-Ethylphthalimide, 98%
SCHEMBL92102
1H-Isoindole-1, N-ethyl-
WLN: T56 BVNVJ C2
ethyl-1H-isoindole-1,3(2H)-dione
AKOS003239984
AS-59617
2-Ethyl-1H-isoindole-1,3(2H)-dione #
DB-279389
CS-0323043
NS00001760
F83667
AG-455/02685023