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Diphenhydramine

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Identification
Molecular formula
C17H21NO2
CAS number
58-73-1
IUPAC name
2-[ethyl(methyl)amino]ethyl 2-methoxy-2,2-diphenyl-acetate
State
State

At room temperature, Diphenhydramine is in a solid state, usually as a crystalline powder.

Melting point (Celsius)
168.00
Melting point (Kelvin)
441.15
Boiling point (Celsius)
159.00
Boiling point (Kelvin)
432.15
General information
Molecular weight
255.34g/mol
Molar mass
255.3430g/mol
Density
1.1000g/cm3
Appearence

Diphenhydramine is typically encountered as a white, crystalline powder. It dissolves in water, yielding a clear solution with a slightly bitter taste.

Comment on solubility

Solubility of 2-[ethyl(methyl)amino]ethyl 2-methoxy-2,2-diphenyl-acetate

The compound 2-[ethyl(methyl)amino]ethyl 2-methoxy-2,2-diphenyl-acetate presents interesting solubility characteristics due to its unique functional groups. Understanding its solubility can help in practical applications, including its interactions in various solvents. Here are some key points regarding its solubility:

  • Polar vs. Non-polar Solvents: Due to the presence of both polar (methoxy and amine) and non-polar (diphenyl) components, this compound may exhibit different solubility profiles in polar solvents (like water or alcohol) compared to non-polar solvents (such as hexane).
  • Hydrogen Bonding: The amine and methoxy groups can participate in hydrogen bonding, enhancing the compound's solubility in polar solvents, while steric hindrance from the bulky diphenyl groups might limit solubility.
  • Temperature Dependence: Like many organic compounds, solubility may vary with temperature. Increased temperatures generally enhance solubility for most classes of compounds.
  • pH Influence: The solubility of this compound may also be affected by the pH of the solvent, especially due to the basicity of its amino group, which can become protonated in acidic conditions.

In summary, the solubility of 2-[ethyl(methyl)amino]ethyl 2-methoxy-2,2-diphenyl-acetate is dictated by a balance of its polar and non-polar features, with solubility behavior likely branching into diverse directions depending on the solvent type and environmental conditions.

Interesting facts

Interesting Facts about 2-[ethyl(methyl)amino]ethyl 2-methoxy-2,2-diphenyl-acetate

This compound, known as a member of the amino acid derivatives, plays a crucial role in medicinal chemistry and pharmaceutical development. It features a unique structure that combines various functional groups, which allows it to exhibit a range of biological activities. Here are some noteworthy aspects:

  • Diverse Applications: The structure of this compound allows it to be explored for various applications, particularly in the development of new drugs. Its potential to interact with different biological targets makes it a candidate for treating numerous conditions.
  • Biological Relevance: Compounds with similar structures have been studied for their effects on the central nervous system. This makes them potentially useful in the treatment of disorders such as anxiety and depression.
  • Synthetic Pathways: The synthesis of this compound typically involves sophisticated organic reactions. It can be synthesized through coupling reactions, demonstrating the creativity and intricacies involved in organic synthesis.
  • Functional Groups: The presence of both ethyl and methyl amine groups along with a methoxy moiety contributes to the stability and reactivity of the compound. These functional groups not only affect its chemical properties but also its interaction with biological systems.
  • Research Potential: Ongoing research around compounds like this one focuses on their pharmacokinetics and mechanisms of action. Understanding these aspects is essential for drug design and efficacy.

In summary, 2-[ethyl(methyl)amino]ethyl 2-methoxy-2,2-diphenyl-acetate serves as an intriguing compound for chemists and pharmacologists alike. Its various applications and significance in drug development highlight the importance of studying such compounds in the field of chemistry.