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Loratadine

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Identification
Molecular formula
C22H23ClN2O2
CAS number
79794-75-5
IUPAC name
2-[ethyl(propyl)amino]ethyl 2-ethoxy-2,2-diphenyl-acetate
State
State

Solid - Loratadine is found in a solid state at room temperature.

Melting point (Celsius)
134.00
Melting point (Kelvin)
407.15
Boiling point (Celsius)
583.30
Boiling point (Kelvin)
856.45
General information
Molecular weight
382.89g/mol
Molar mass
382.8850g/mol
Density
1.0070g/cm3
Appearence

Loratadine is a white to off-white crystalline powder.

Comment on solubility

Solubility Characteristics of 2-[ethyl(propyl)amino]ethyl 2-ethoxy-2,2-diphenyl-acetate

The solubility of 2-[ethyl(propyl)amino]ethyl 2-ethoxy-2,2-diphenyl-acetate in various solvents can be quite intriguing due to its complex structure. This compound exhibits interesting behavior in both polar and non-polar environments. Here are some key points to consider:

  • Polar Solvents: Compounds with amino groups tend to show increased solubility in polar solvents, such as water and alcohols, due to hydrogen bonding interactions.
  • Non-Polar Solvents: The presence of large hydrophobic phenyl groups suggests that 2-[ethyl(propyl)amino]ethyl 2-ethoxy-2,2-diphenyl-acetate may also dissolve readily in non-polar solvents like hexane and chloroform.
  • Temperature Dependence: Like many organic compounds, the solubility is likely to vary with temperature—generally, an increase in temperature will enhance solubility.
  • pH Influence: Given its amino functionality, the solubility could be affected by the pH of the solution, with increased solubility in more basic environments where the amino group can become protonated.

In conclusion, the solubility profile of 2-[ethyl(propyl)amino]ethyl 2-ethoxy-2,2-diphenyl-acetate is complex, influenced by both its polar and non-polar characteristics and its interactions with the solvent. As stated, "Solubility is a dance of interactions," and this compound certainly exhibits a graceful performance across diverse chemical environments.

Interesting facts

2-[ethyl(propyl)amino]ethyl 2-ethoxy-2,2-diphenyl-acetate

This fascinating compound, known as 2-[ethyl(propyl)amino]ethyl 2-ethoxy-2,2-diphenyl-acetate, belongs to a class of chemicals that exhibit diverse pharmacological activities. Here are some intriguing facts about it:

  • Structure and Function: The compound features both an ethyl and a propyl moiety as part of its amino group, which can significantly influence its biological interactions. The presence of diphenyl groups also suggests a potential for unique binding properties.
  • Potential Applications: Compounds with similar structures are often investigated for their use in the pharmaceutical industry. They can act as intermediates in the synthesis of drug molecules or may possess direct medicinal properties.
  • Research Interest: Due to its complex structure, this compound may be a subject of interest in the fields of medicinal chemistry and organic synthesis. Researchers strive to understand how alterations in functional groups can lead to changes in activity.
  • Educational Value: For chemistry students, exploring this compound can provide insights into the principles of structural activity relationships (SAR), which is the relationship between the chemical structure of a compound and its biological activity.

In the world of organic chemistry, compounds like this one serve as a reminder of the intricate connections between molecular structure and function. As the field continues to evolve, the exploration of such compounds will undoubtedly contribute to numerous advancements in science and medicine.