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Diphenoxylate

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Identification
Molecular formula
C30H32ClNO2
CAS number
915-30-0
IUPAC name
2-[ethyl(propyl)amino]ethyl 2-hydroxy-2,2-diphenyl-acetate
State
State

At room temperature, diphenoxylate is in a solid state. Its crystalline powder form is stable under standard conditions, typically requiring no special handling procedures to maintain its solid state.

Melting point (Celsius)
223.00
Melting point (Kelvin)
496.15
Boiling point (Celsius)
555.30
Boiling point (Kelvin)
828.50
General information
Molecular weight
452.55g/mol
Molar mass
452.5460g/mol
Density
1.2240g/cm3
Appearence

Diphenoxylate typically appears as a white or off-white crystalline powder. The compound is often odorless, making it challenging to identify through smell alone. Its solid crystalline form is a characteristic feature, and it may display a slight sheen under specific lighting conditions.

Comment on solubility

Solubility of 2-[ethyl(propyl)amino]ethyl 2-hydroxy-2,2-diphenyl-acetate

The solubility of 2-[ethyl(propyl)amino]ethyl 2-hydroxy-2,2-diphenyl-acetate can be influenced by several factors. Understanding its solubility is crucial for applications in both laboratory and industrial settings. Here are some key points to consider:

  • Polarity: The presence of polar functional groups, such as the hydroxyl (-OH) group, typically enhances solubility in polar solvents like water.
  • Hydrophobic interactions: The diphenyl groups may contribute to hydrophobic characteristics, which could limit solubility in highly polar solvents but enhance solubility in non-polar organic solvents.
  • Temperature: Generally, an increase in temperature may enhance solubility by allowing more molecules to dissolve. Observing this compound's behavior over a range of temperatures can offer valuable insights.
  • pH dependence: If the compound can exist in ionized or unionized forms under different pH conditions, this could significantly affect its solubility in aqueous solutions.

In summary, the solubility of 2-[ethyl(propyl)amino]ethyl 2-hydroxy-2,2-diphenyl-acetate is a complex interplay of molecular structure, polarity, temperature, and environmental conditions. Investigating its solubility behavior not only aids in its application but also enhances our understanding of the compound's chemical properties.

Interesting facts

Interesting Facts about 2-[ethyl(propyl)amino]ethyl 2-hydroxy-2,2-diphenyl-acetate

This compound, 2-[ethyl(propyl)amino]ethyl 2-hydroxy-2,2-diphenyl-acetate, is a fascinating example of synthetic organic chemistry, exemplifying how diverse functional groups can be incorporated into a single molecular structure. Its complexity arises from the presence of multiple substituents, which can lead to interesting biochemical interactions.

Significance in Organic Chemistry

Versatile Structure: The structure features an amino group, a hydroxy group, and multiple aromatic rings, making it a prime candidate for studies in medicinal chemistry and pharmacology. Each element contributes to the compound's reactivity and potential biological activity.

  • Amino Group: The ethyl and propyl substitutions indicate a branched amine, which may enhance lipophilicity, thus affecting how readily the compound can permeate biological membranes.
  • 2-Hydroxy Group: The presence of a hydroxy group can increase solubility in polar solvents and may also engage in hydrogen bonding, influencing the compound's overall stability and interaction capabilities.
  • Diphenyl Moiety: The diphenyl structure plays a critical role in modulating the physicochemical properties of the compound, frequently contributing to its applications in pharmaceuticals as well as material science.

Potential Applications

This compound could inspire new developments in drug design and delivery systems. By modifying its structure, chemists can tailor its properties for specific therapeutic targets. Research into similar compounds reveals that they may act as:

  • Analgesics, providing pain relief
  • Anti-inflammatory agents, targeting inflammation
  • Potential neuroprotective agents, offering protection against neuronal damage

In the realm of synthetic organic chemistry, compounds like this serve as critical models for understanding structure-activity relationships, which are vital for developing new drugs. As one researcher noted, "The complexity of such molecules is both a challenge and an opportunity for discovery." Through continuous study, the potential impacts of this compound could expand significantly, leading to innovative solutions in various fields.


Synonyms
Benapryzine
BENAPRIZINE
Benaprizine [INN:BAN]
UNII-14FPC4V3AX
14FPC4V3AX
22487-42-9
benaprizina
BENAPRYZINE [MI]
BENAPRIZINE [INN]
2-(ETHYLPROPYLAMINO)ETHYL BENZILATE
Benzeneacetic acid, .alpha.-hydroxy-.alpha.-phenyl-, 2-(ethylpropylamino)ethyl ester
benaprizinum
BENZENEACETIC ACID, ALPHA-HYDROXY-ALPHA-PHENYL-, 2-(ETHYLPROPYLAMINO)ETHYL ESTER
2-[ethyl(propyl)amino]ethyl 2-hydroxy-2,2-diphenylacetate
2-(ethyl(propyl)amino)ethyl 2-hydroxy-2,2-diphenylacetate
SCHEMBL250007
CHEMBL2110766
DTXSID00865055
CHEBI:191253
2-[ethyl(propyl)amino]ethyl hydroxy(diphenyl)acetate
Q27251623