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2-Fluoroacetophenone

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Identification
Molecular formula
C8H7FO
CAS number
450-89-5
IUPAC name
2-fluoro-1-phenyl-ethanone
State
State

At room temperature, 2-Fluoroacetophenone is a liquid.

Melting point (Celsius)
-18.00
Melting point (Kelvin)
255.15
Boiling point (Celsius)
195.00
Boiling point (Kelvin)
468.15
General information
Molecular weight
138.14g/mol
Molar mass
138.1380g/mol
Density
1.1340g/cm3
Appearence

2-Fluoroacetophenone appears as a colorless to pale yellow liquid. It may have a sharp and sometimes pleasant odor.

Comment on solubility

Solubility of 2-fluoro-1-phenyl-ethanone

2-fluoro-1-phenyl-ethanone, with the chemical formula C8H8F1O1, exhibits notable characteristics regarding its solubility in various solvents. Generally, the solubility of this compound can be influenced by several factors:

  • Polarity: 2-fluoro-1-phenyl-ethanone has both polar and non-polar characteristics due to the presence of the fluorine atom and the phenyl group. This allows for moderate solubility in polar solvents such as water and ethanol.
  • Temperature: The solubility of organic compounds often increases with temperature. So, heating the solvent can enhance the solubility of 2-fluoro-1-phenyl-ethanone.
  • Hydrogen Bonding: The compound may engage in hydrogen bonding interactions with solvents that have hydroxyl groups, thus enhancing its solubility.

In general, it is observed that:

  1. 2-fluoro-1-phenyl-ethanone is soluble in organic solvents such as acetone, chloroform, and ether.
  2. It is partially soluble in water, indicating that while some dissolution occurs, it is not significant.

Overall, the solubility profile of 2-fluoro-1-phenyl-ethanone demonstrates interesting interactions that can be exploited in various chemical applications. Understanding the solubility behavior is crucial for its effective use in synthesis and other reactions.

Interesting facts

Interesting Facts about 2-fluoro-1-phenyl-ethanone

2-fluoro-1-phenyl-ethanone, also known as (2-fluorophenyl) ethyl ketone, is a fascinating compound with unique properties and applications in the field of organic chemistry. Here are some noteworthy facts:

  • Fluorinated Compounds: The presence of the fluorine atom in its structure introduces significant changes in reactivity and polarity. This can enhance the compound's biological activity, making it a candidate for drug development.
  • Ketones in Synthesis: Ketones are vital in various chemical reactions, particularly in the synthesis of more complex organic molecules. 2-fluoro-1-phenyl-ethanone can serve as an intermediate in the production of pharmaceuticals and agrochemicals.
  • Applications in Research: Scientists utilize this compound as a building block for creating novel materials and studying reaction mechanisms, often in the development of fluorinated pharmaceuticals.
  • Safety Considerations: As with many organic compounds, understanding the safety protocols for handling 2-fluoro-1-phenyl-ethanone is crucial. Proper laboratory practices ensure that researchers can work effectively and safely.
  • Environmental Implications: The behavior of fluorinated compounds in the environment is an area of active research, as they can display persistence. Exploring the environmental fate of 2-fluoro-1-phenyl-ethanone helps clarify its impact.

In summary, 2-fluoro-1-phenyl-ethanone represents a blend of intriguing chemical properties and practical applications, making it a compound of interest for both industrial and academic pursuits. As one chemist aptly stated, "Fluorine is often the element of choice when fine-tuning the properties of organic compounds." This underscores the compound's importance in advancing chemical science.

Synonyms
2-Fluoroacetophenone
2-Fluoro-1-phenylethanone
450-95-3
Phenacyl fluoride
2-Fluoro-1-phenylethan-1-one
Ethanone, 2-fluoro-1-phenyl-
alpha-Fluoroacetophenone
ACETOPHENONE, 2-FLUORO-
C8H7FO
fluoromethyl phenyl ketone
fluoroacetophenone
1-Fluoroacetophenone
EINECS 207-190-6
BRN 1858991
fluoro-acetophenone
MFCD08461612
(fluoroacetyl)benzene
2-fluoro acetophenone
2-fluoro-acetophenone
AJ3PQL86NX
2-fluoro-1-phenyl-ethanone
SCHEMBL157987
2-fluoro-1-phenyl ethan-1-one
DTXSID90196360
AKOS006343501
FF77422
AS-39535
DB-347050
CS-0037091
NS00042954
EN300-1272026
2-Fluoro-1-phenylethan-1-one; 2-Fluoroacetophenone
207-190-6