2-Fluoro-6,11-dihydrothiochromeno[4,3-b]indole

Identification

Molecular formula

C₁₅H₁₂FNO₁S₁

CAS number

.cc1c2c3ccc(cc3)SCCCC5c6c1c(F)c(n6)c5c2

IUPAC name

2-fluoro-6,11-dihydrothiochromeno[4,3-b]indole

State

The compound is typically in a solid state at room temperature.

Melting point (Celsius)

188.00

Melting point (Kelvin)

461.15

Boiling point (Celsius)

420.00

Boiling point (Kelvin)

693.15

General information

Molecular weight

281.35g/mol

Molar mass

281.3500g/mol

Density

1.3200g/cm³

Appearence

The compound appears as a crystalline solid. The specific appearance may vary slightly depending on the particular synthesis and purity, but it typically manifests as white to pale yellow crystals.

Comment on solubility

Solubility of 2-fluoro-6,11-dihydrothiochromeno[4,3-b]indole

The solubility of 2-fluoro-6,11-dihydrothiochromeno[4,3-b]indole is an intriguing aspect that warrants exploration. As a complex organic compound, its solubility is influenced by several factors:

Polarity: Typically, organic compounds with greater polarity exhibit higher solubility in polar solvents such as water.
Hydrogen Bonding: The ability of the compound to engage in hydrogen bonding can enhance its solubility in appropriate solvents.
Functional Groups: The presence of functional groups plays a significant role; for instance, fluorine substitutions can impact solubility behavior.

However, the solubility of 2-fluoro-6,11-dihydrothiochromeno[4,3-b]indole is generally considered to be moderate in organic solvents but lower in water. In practical applications, this solubility can limit its use in aqueous environments.

As a general guideline, it is valuable to remember:

Try dissolving in: DMSO, methanol, or ethanol for optimal results.
Avoid: Using water as a solvent due to expected low solubility.

Understanding the solubility features of such compounds is crucial for their practical application in fields like pharmaceuticals and materials science.

Interesting facts

Interesting Facts about 2-Fluoro-6,11-dihydrothiochromeno[4,3-b]indole

2-Fluoro-6,11-dihydrothiochromeno[4,3-b]indole is a fascinating compound that draws attention from both organic chemists and medicinal researchers. Its unique structure offers a range of potential applications and interesting chemical behavior:

Diverse Structure: This compound features a thiochromene ring fused with an indole structure, setting it apart from more common organic compounds. The incorporation of a fluorine atom enhances its reactivity and can influence biological activity.
Potential Biological Activities: Compounds with indole frameworks are often investigated for their pharmacological properties. This particular compound may exhibit properties that could be relevant in drug development, especially in targeting neural and inflammatory conditions.
Versatile Synthesis: The synthesis of thiochromenoindole derivatives generally involves intricate multi-step processes, showcasing the creativity required in organic synthesis. Chemists often utilize techniques like cyclization and functional group transformations to construct such complex molecules.
Fluorination Significance: The presence of the fluorine atom in the structure is significant; fluorinated compounds are known for their unique electronic properties, which can lead to improved drug metabolic stability and bioavailability.
Research Continues: Ongoing research into the thiochromene family may reveal even more bioactive derivatives, making the understanding of this compound vital for future studies in medicinal chemistry.

As chemistry continues to advance, compounds like 2-fluoro-6,11-dihydrothiochromeno[4,3-b]indole remind us of the complex and beautiful world of organic chemistry, highlighting the interplay between structure and function in chemical compounds.

Synonyms

(1)BENZOTHIOPYRANO(4,3-b)INDOLE, 6,11-DIHYDRO-2-FLUORO-

22298-04-0

BRN 1582713

6,11-Dihydro-2-fluoro-(1)benzothiopyrano(4,3-b)indole

Thiopyrano(4,3-b)benz(e)indole, 6,11-dihydro-2-fluoro-

DTXSID90176844